Cancer Family
Esophageal Neoplasm
CI-CAN-00000174Explore in graph →
Non-malignant555 active trials6 approved drugs12 evidence items
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Cancer Family
CI-CAN-00000174Explore in graph →
Clinical trials
2,208 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06317272 | BReath Hold TecHniquEs for Radiotherapy of Esophageal Carcinoma(BROTHER) | terminated | N/A | 1 | University Medical Center GroningenOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT04244552 | A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies | terminated | Phase 1 | 87 | Atreca, Inc.INDUSTRY | 1 | Dec 29, 2023 | clinicaltrials |
| NCT04187872 | LITT and Pembrolizumab in Recurrent Brain Metastasis(TORCH) | terminated | Phase 1 | 10 | University of FloridaOTHER | 1 | Dec 27, 2023 | clinicaltrials |
| NCT05579444 | Systems Biology of Gastrointestinal and Related Diseases | terminated | — | 17 | ViomeINDUSTRY | 1 | Dec 15, 2023 | clinicaltrials |
| NCT01307956 | Panitumumab, Combination Chemotherapy, & Radiation Therapy in Esophageal or Gastroesophageal Junction Cancer | terminated | Phase 2 | 11 | University of NebraskaOTHER | 1 | Oct 26, 2023 | clinicaltrials |
| NCT01366833 | Optimal Management of Malignant Dysphagia | terminated | N/A | 3 | McGill University Health Centre/Research Institute of the McGill University Health CentreOTHER | 1 | Oct 23, 2023 | clinicaltrials |
| NCT04424641 | A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors | terminated | Phase 1 / Phase 2 | 48 | GenmabINDUSTRY | 4 | Jul 25, 2023 | clinicaltrials |
| NCT02530437 | Taladegib, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Localized Esophageal or Gastroesophageal Junction Cancer | terminated | Phase 1 / Phase 2 | 7 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 10, 2023 | clinicaltrials |
| NCT00551759 | Chemotherapy, Radiation Therapy, and Cetuximab Followed by Surgery, Docetaxel, and Cetuximab in Treating Patients With Esophageal Cancer or Gastroesophageal Junction Cancer | terminated | Phase 2 | 22 | Eastern Cooperative Oncology GroupNETWORK | 1 | Jul 3, 2023 | clinicaltrials |
| NCT02489201 | A Study of Donafenib Monotherapy in Advanced Oesophageal Cancer | terminated | Phase 1 / Phase 2 | 19 | Suzhou Zelgen Biopharmaceuticals Co.,LtdINDUSTRY | 1 | Jun 15, 2023 | clinicaltrials |
| NCT03233724 | Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas | terminated | Phase 1 / Phase 2 | 9 | National Cancer Institute (NCI)NIH | 1 | May 31, 2023 | clinicaltrials |
| NCT03385343 | Staging of Superficial EAC Using VLE | terminated | N/A | 30 | Mayo ClinicOTHER | 1 | May 9, 2023 | clinicaltrials |
| NCT02988934 | The WATS3D (Wide Area Transepithelial Sample Biopsy With 3-Dimensional Computer-Assisted Analysis) U.S. Registry | terminated | — | 3,173 | CDx DiagnosticsINDUSTRY | 1 | Feb 8, 2023 | clinicaltrials |
| NCT03240679 | Endoscopic Mucosal Resection and Cellular Matrix | terminated | N/A | 3 | Mayo ClinicOTHER | 1 | Feb 6, 2023 | clinicaltrials |
| NCT03251417 | Apatinib and Irinotecan Combination Treatment in Unresectable or Metastatic Esophageal Squamous Cell Carcinoma | terminated | Phase 2 | 11 | Peking UniversityOTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT04510285 | A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection | terminated | Phase 2 | 1 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 1, 2023 | clinicaltrials |
| NCT04077372 | Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers | terminated | N/A | 12 | Stanford UniversityOTHER | 1 | Jan 27, 2023 | clinicaltrials |
| NCT03570996 | A Trial Comparing Transversus Abdominis Plane Catheter Versus Epidural After Esophagectomy | terminated | N/A | 38 | Swedish Medical CenterOTHER | 1 | Jan 23, 2023 | clinicaltrials |
| NCT04415463 | Esophageal Multisegmented FCSEMS for Malignant Strictures(EATERS) | terminated | N/A | 23 | Radboud University Medical CenterOTHER | 1 | Jan 12, 2023 | clinicaltrials |
| NCT04642690 | Nitrates and IL-8 in Barrett's Esophagus | terminated | — | 9 | Mayo ClinicOTHER | 1 | Dec 15, 2022 | clinicaltrials |
| NCT04060342 | GB1275 Monotherapy and in Combination With an Anti-PD1 Antibody in Patients With Specified Advanced Solid Tumors or in Combination With Standard of Care in Patients With Metastatic Pancreatic Adenocarcinoma | terminated | Phase 1 | 61 | GB006, Inc., a wholly owned subsidiary of Gossamer Bio, Inc.INDUSTRY | 2 | Aug 18, 2022 | clinicaltrials |
| NCT00573131 | Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer | terminated | Phase 2 | 137 | Boston Scientific CorporationINDUSTRY | 4 | Jun 22, 2022 | clinicaltrials |
| NCT02859415 | Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases | terminated | Phase 1 / Phase 2 | 3 | National Cancer Institute (NCI)NIH | 1 | Apr 5, 2022 | clinicaltrials |
| NCT03278626 | Immune Checkpoint Therapy With Nivolumab Esophageal Squamous Cell Carcinoma | terminated | Phase 1 / Phase 2 | 12 | NYU Langone HealthOTHER | 1 | Mar 28, 2022 | clinicaltrials |
| NCT01868139 | Spray Cryotherapy for Esophageal Cancer (ICE-CANCER)(ICE-CANCER) | terminated | N/A | 1 | University of Maryland, BaltimoreOTHER | 1 | Mar 7, 2022 | clinicaltrials |
| NCT00321958 | Study of Cryotherapy Treatment of Barrett's Esophagus and Early Esophageal Cancer | terminated | — | 23 | University of Maryland, BaltimoreOTHER | 1 | Feb 8, 2022 | clinicaltrials |
| NCT01445327 | Predictors of Tumor Response and of Radiation Therapy Side Effects in Patients With Gastrointestinal Cancers | terminated | — | 9 | National Cancer Institute (NCI)NIH | 1 | Feb 1, 2022 | clinicaltrials |
| NCT02999893 | A Study of APR-246 in Oesophageal Cancer(APROC) | terminated | Phase 1 / Phase 2 | 5 | Peter MacCallum Cancer Centre, AustraliaOTHER | 1 | Dec 13, 2021 | clinicaltrials |
| NCT01806649 | BKM120 in Esophageal Squamous Cell Carcinoma After Failure of First Line Chemotherapy | terminated | Phase 2 | 5 | Prince of Songkla UniversityOTHER | 1 | Oct 11, 2021 | clinicaltrials |
| NCT00003487 | Antineoplaston Therapy in Treating Patients With Cancer of the Esophagus | terminated | Phase 2 | 8 | Burzynski Research InstituteOTHER | 1 | May 14, 2021 | clinicaltrials |
| NCT04086901 | Dose Escalated Adaptive RadioTherapy in Definitive Chemo-radiotherapy for Esophageal Cancer(DART) | terminated | N/A | 3 | University of AarhusOTHER | 1 | Mar 9, 2021 | clinicaltrials |
| NCT02864355 | Does Perioperative Goal Directed Therapy Using Flotrac Improve Outcomes in Esophagectomy Patients | terminated | N/A | 53 | Medical University of South CarolinaOTHER | 1 | Mar 2, 2021 | clinicaltrials |
| NCT00064259 | A Phase I/II Study of Oblimersen Plus Cisplatin and Fluorouracil in Gastric & Esophageal Junction Cancer | terminated | Phase 1 / Phase 2 | 15 | National Cancer Institute (NCI)NIH | 1 | Feb 17, 2021 | clinicaltrials |
| NCT02774551 | Physical Activity Intervention Trial to Mitigate Muscle Loss and Increase Muscle Strength | terminated | N/A | 162 | Karolinska InstitutetOTHER | 1 | Dec 14, 2020 | clinicaltrials |
| NCT02757391 | CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors | terminated | Phase 1 | 1 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 30, 2020 | clinicaltrials |
| NCT02297607 | Routine Post-Operative Supplemental Nutrition | terminated | N/A | 30 | University of MichiganOTHER | 1 | Aug 27, 2020 | clinicaltrials |
| NCT00006472 | Combination Chemotherapy Plus Radiation Therapy Followed By Surgery in Treating Patients With Stage I, Stage II, or Stage III Esophageal Cancer | terminated | Phase 2 | 4 | Medstar Health Research InstituteOTHER | 1 | Aug 18, 2020 | clinicaltrials |
| NCT01249443 | Paclitaxel and Carboplatin in Treating Patients With Metastatic or Recurrent Solid Tumors and HIV Infection | terminated | Phase 1 | 17 | AIDS Malignancy ConsortiumNETWORK | 1 | Jul 29, 2020 | clinicaltrials |
| NCT02017600 | A Phase II Trial of Induction Chemotherapy With ND-420, Cisplatin and Fluorouracil Followed by Surgery in the Treatment of Patients With Localized Squamous Cell Carcinoma of the Esophagus | terminated | Phase 2 | 48 | Nang Kuang Pharmaceutical Co., Ltd.INDUSTRY | 1 | May 20, 2020 | clinicaltrials |
| NCT03206125 | NCI UNC Project ESCC | terminated | — | 648 | National Cancer Institute (NCI)NIH | 1 | May 20, 2020 | clinicaltrials |
| NCT01361750 | The Effects of Gastric Tube on the Quality of Life and Nutritional Status After Ivor-Lewis Esophagectomy | terminated | N/A | 21 | Peking UniversityOTHER | 1 | Mar 31, 2020 | clinicaltrials |
| NCT00539617 | Chemotherapy & Erlotinib in Treating Patients w/ Esophageal or Gastroesophageal Cancer That Cannot Be Removed by Surgery | terminated | Phase 2 | 7 | University of California, San FranciscoOTHER | 1 | Mar 23, 2020 | clinicaltrials |
| NCT02601079 | Endodrill vs. Conventional Biopsy. Diagnostics and Genetic Analysis | terminated | N/A | 7 | Region SkaneOTHER | 1 | Mar 17, 2020 | clinicaltrials |
| NCT01143545 | Pilot Study of Allogeneic Tumor Cell Vaccine With Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers, Thymic Neoplasms, and Malignant Pleural Mesotheliomas | terminated | Phase 1 | 10 | National Cancer Institute (NCI)NIH | 1 | Mar 3, 2020 | clinicaltrials |
| NCT01624090 | Mithramycin for Lung, Esophagus, and Other Chest Cancers | terminated | Phase 2 | 16 | National Cancer Institute (NCI)NIH | 1 | Dec 30, 2019 | clinicaltrials |
| NCT00585117 | Pilot Study of (61)CuATSM-PET Imaging in Cancer Patients | terminated | N/A | 9 | University of Wisconsin, MadisonOTHER | 1 | Dec 13, 2019 | clinicaltrials |
| NCT00094978 | Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum | terminated | Phase 1 | 23 | National Cancer Institute (NCI)NIH | 1 | Dec 12, 2019 | clinicaltrials |
| NCT01258868 | Tumor Cell Vaccines With ISCOMATRIX Adjuvant and Celecoxib in Patients Undergoing Resection of Lung and Esophageal Cancers and Malignant Pleural Mesotheliomas | terminated | Phase 1 | 44 | National Cancer Institute (NCI)NIH | 1 | Dec 3, 2019 | clinicaltrials |
| NCT02318901 | Pembrolizumab and Monoclonal Antibody Therapy in Advanced Cancer(PembroMab) | terminated | Phase 1 / Phase 2 | 16 | Western Regional Medical CenterOTHER | 1 | Oct 21, 2019 | clinicaltrials |
| NCT02721550 | A Trial of CMNa Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced ESCC | terminated | Phase 4 | 2 | Shandong Cancer Hospital and InstituteOTHER | 1 | Oct 11, 2019 | clinicaltrials |
Data updated 22 days agoSource updated Mar 19, 2024source: clinicaltrials