Histology
Endometrioid Adenocarcinoma
CI-CAN-00000839Explore in graph →
55 active trials1 evidence items
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Histology
CI-CAN-00000839Explore in graph →
Variants & evidence
1 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| BRCA1 W1815X1 | ||||||||
| Olaparib | Ovarian Endometrioid AdenocarcinomaALIAS | Predictive | D | Supports Sensitivity Response | 2 | accepted | EID4623In an in vitro study, a SNU-251 cell line expressing BRCA1 W1815X truncating mutation demonstrated increased sensitivity to olaparib treatment with long-term exposure, compared to ovarian cell lines e… (full text at CIViC) PMID 23415752 · Stordal et al., 2013 · Open in CIViC | civic |
Data updated 16 hours agoSource updated unknownsource: civic (CC0)
Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.