Cancer Family
Connective and Soft Tissue Neoplasm
CI-CAN-00000010Explore in graph →
Non-malignant849 active trials17 approved drugs339 evidence items
Loading cancer entity…
Loading cancer entity…
Cancer Family
CI-CAN-00000010Explore in graph →
Clinical trials
3,878 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04925609 | Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors(Briga-PED) | recruiting | Phase 1 / Phase 2 | 65 | Princess Maxima Center for Pediatric OncologyOTHER | 2 | Dec 5, 2025 | clinicaltrials |
| NCT05120271 | BOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors(DUET-1) | active not recruiting | Phase 1 / Phase 2 | 7 | Sotio Biotech Inc.INDUSTRY | 2 |
| Dec 5, 2025 |
| clinicaltrials |
| NCT07267780 | Contribution of Oncovascular Surgery in the Treatment of Gynecological Advanced Malignant Diseases. | not yet recruiting | — | 130 | National Cancer Institute, NaplesOTHER | 1 | Dec 5, 2025 | clinicaltrials |
| NCT01991379 | MEK162 in Combination With Imatinib Mesylate in Patients With Untreated Advanced Gastrointestinal Stromal Tumor (GIST) | active not recruiting | Phase 1 / Phase 2 | 75 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT02307630 | PET Imaging of Solid Tumors Using 124I-Humanized 3F8: A Pilot Study | active not recruiting | N/A | 7 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT05301283 | Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma | recruiting | Phase 2 | 43 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT07264296 | Implant-Related Infections in Patients With Skeletal Sarcomas(IRISSAR) | enrolling by invitation | — | 40 | Vastra Gotaland RegionOTHER_GOV | 1 | Dec 4, 2025 | clinicaltrials |
| NCT02869217 | Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors | active not recruiting | Phase 1 | 22 | University Health Network, TorontoOTHER | 1 | Dec 3, 2025 | clinicaltrials |
| NCT02789384 | CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study.(NEOSarcomics) | recruiting | N/A | 205 | Institut BergoniéOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT03834961 | Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia | active not recruiting | Phase 2 | 33 | Children's Oncology GroupNETWORK | 2 | Dec 2, 2025 | clinicaltrials |
| NCT03889899 | Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia. | recruiting | N/A | 30 | Alpha Tau Medical LTD.INDUSTRY | 1 | Dec 2, 2025 | clinicaltrials |
| NCT06333314 | Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI(Pan-MSI-ACSE) | recruiting | Phase 2 | 120 | UNICANCEROTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT06941194 | Preventive Application of Single-use Negative Pressure Wound Therapy (sNPWT) in the Postoperative Course of Radiotreatated Limb Sarcoma Surgery(PRALISS) | recruiting | N/A | 48 | Istituto Oncologico Veneto IRCCSOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT07027423 | BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas | not yet recruiting | Phase 1 | 32 | University Health Network, TorontoOTHER | 1 | Dec 1, 2025 | clinicaltrials |
| NCT02811523 | In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma | recruiting | Phase 1 | 17 | University Health Network, TorontoOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT04388839 | Evolutionary Therapy for Rhabdomyosarcoma | active not recruiting | Phase 2 | 12 | H. Lee Moffitt Cancer Center and Research InstituteOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT07250334 | Prospective Phase I/II Study Evaluating the Safety and Efficacy of Preoperative Carbon Ion Radiotherapy in Patients With Soft Tissue Sarcoma : The SARCOMA-01 Trial by the Severance sARCOma Multidisciplinary Team(SARCOMA-01) | not yet recruiting | N/A | 60 | Yonsei UniversityOTHER | 1 | Nov 26, 2025 | clinicaltrials |
| NCT01117168 | Enrollment on the Childhood Cancer Research Network (CCRN) of the Children's Oncology Group | active not recruiting | — | 57,816 | Children's Oncology GroupNETWORK | 1 | Nov 24, 2025 | clinicaltrials |
| NCT06988475 | DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations(DETERMINE) | recruiting | Phase 2 / Phase 3 | 30 | Cancer Research UKOTHER | 1 | Nov 24, 2025 | clinicaltrials |
| NCT04081701 | 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.(DOMINO-START) | recruiting | Phase 4 | 200 | Weill Medical College of Cornell UniversityOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT05238883 | A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors | active not recruiting | Phase 1 | 72 | HiFiBiO TherapeuticsINDUSTRY | 2 | Nov 21, 2025 | clinicaltrials |
| NCT06930846 | HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)(HOBSCOTCH-CA) | recruiting | N/A | 125 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT03618381 | EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | active not recruiting | Phase 1 | 44 | Seattle Children's HospitalOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT04133285 | Registry of Multiple Osteochondromas(REM) | recruiting | — | 10,000 | Luca SangiorgiOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT05312411 | A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma | active not recruiting | Phase 1 | 21 | Seattle Children's HospitalOTHER | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06375941 | Prospective Observational Study of Localized Angiosarcoma of Any Site: ProStars(ProStars) | recruiting | — | 250 | Italian Sarcoma GroupNETWORK | 1 | Nov 20, 2025 | clinicaltrials |
| NCT06081400 | Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting(CRYODESMO-02) | recruiting | N/A | 150 | University Hospital, Strasbourg, FranceOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT06939855 | QL1706 in the Treatment of Advanced Bone and Soft Tissue Sarcoma | recruiting | Phase 2 | 45 | Sun Yat-sen UniversityOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT07230444 | Artificial Intelligence for the Intra-procedural Assessment of Uterine Artery Embolization(AI-EMBO) | not yet recruiting | — | 250 | Emanuele BarabinoOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT07235787 | Efficacy of Ultrasound Guided Microwave Ablation in the Treatment of Uterine Fibroids.(MWAUF) | not yet recruiting | N/A | 20 | Jihad Hussien Mohamed MahmoudOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT03099681 | An Observational Study on Epithelioid Sarcoma(EPISObs) | recruiting | — | 100 | Italian Sarcoma GroupNETWORK | 1 | Nov 18, 2025 | clinicaltrials |
| NCT05812027 | A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors | active not recruiting | — | 1,150 | TScan Therapeutics, Inc.INDUSTRY | 1 | Nov 17, 2025 | clinicaltrials |
| NCT07227961 | PROMIS and Mobility Evaluation in Sarcoma Patients | recruiting | — | 800 | University of CalgaryOTHER | 2 | Nov 13, 2025 | clinicaltrials |
| NCT04551430 | Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma | active not recruiting | Phase 2 | 105 | Washington University School of MedicineOTHER | 1 | Nov 12, 2025 | clinicaltrials |
| NCT06521567 | A Study of Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer | active not recruiting | Phase 1 / Phase 2 | 83 | GlaxoSmithKlineINDUSTRY | 6 | Nov 12, 2025 | clinicaltrials |
| NCT03173976 | Anti-Osteoclast Therapy as Neoadjuvant in Treatment of Chondrosarcoma - Phase 1b Trial | active not recruiting | Phase 1 | 17 | Mohammed MilhemOTHER | 1 | Nov 6, 2025 | clinicaltrials |
| NCT07129317 | Pediatric Radiation Therapy Registry | recruiting | — | 5,000 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Nov 5, 2025 | clinicaltrials |
| NCT00996710 | Genomic Structural Variation in Cancer Susceptibility | active not recruiting | — | 1,275 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Nov 4, 2025 | clinicaltrials |
| NCT01223248 | Randomized Study Comparing Two Dosing Schedules for Hypofractionated Image-Guided Radiation Therapy | active not recruiting | Phase 3 | 220 | Memorial Sloan Kettering Cancer CenterOTHER | 3 | Nov 4, 2025 | clinicaltrials |
| NCT07224568 | Cytokine Armored GPC3 Specific Chimeric Antigen Receptor Expressing T-cells in Adults With Solid Tumors(INTERCEPT) | not yet recruiting | Phase 1 | 21 | Seattle Children's HospitalOTHER | 1 | Nov 4, 2025 | clinicaltrials |
| NCT06198296 | Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells | recruiting | Phase 1 | 21 | Baylor College of MedicineOTHER | 1 | Nov 3, 2025 | clinicaltrials |
| NCT04803877 | SARC038: Phase 2 Study of Regorafenib and Nivolumab in Osteosarcoma | active not recruiting | Phase 2 | 48 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Oct 31, 2025 | clinicaltrials |
| NCT06208748 | SARC044: A Phase II Trial of Bezuclastinib in Combination With Sunitinib in Patients With GIST | active not recruiting | Phase 2 | 40 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | Oct 31, 2025 | clinicaltrials |
| NCT05886634 | A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma | active not recruiting | Phase 2 | 16 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Oct 20, 2025 | clinicaltrials |
| NCT02508038 | Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors | recruiting | Phase 1 | 22 | University of Wisconsin, MadisonOTHER | 1 | Oct 16, 2025 | clinicaltrials |
| NCT03160274 | Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions | recruiting | — | 2,000 | The University of Texas Health Science Center at San AntonioOTHER | 1 | Oct 15, 2025 | clinicaltrials |
| NCT07058064 | WATCH (Wearable Artificial inTelligence for Cardiac Function and Health Monitoring) | recruiting | N/A | 250 | Mayo ClinicOTHER | 1 | Oct 15, 2025 | clinicaltrials |
| NCT06812052 | Short Course Radiation Treatment for Patients With Primary or Locally Recurrent Retroperitoneal Sarcoma Prior to Surgery | recruiting | Phase 1 | 6 | Brigham and Women's HospitalOTHER | 1 | Oct 14, 2025 | clinicaltrials |
| NCT04370587 | A Clinical Study of Intratumoral MVR-T3011 (T3011) Given as a Single Agent and in Combination With Intravenous Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors | recruiting | Phase 1 / Phase 2 | 30 | ImmVira Pharma Co. LtdINDUSTRY | 2 | Oct 8, 2025 | clinicaltrials |
| NCT05182164 | Combination of Pembrolizumab and Cabozantinib in Patients With Advanced Sarcomas(PEMBROCABOSARC) | recruiting | Phase 2 | 119 | Institut BergoniéOTHER | 1 | Oct 7, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Dec 5, 2025source: clinicaltrials