Hematologic Malignancy
B-Cell Non-Hodgkin Lymphoma
CI-CAN-00000471Explore in graph →
Hematologic1,757 active trials43 approved drugs73 evidence items
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Hematologic Malignancy
CI-CAN-00000471Explore in graph →
Clinical trials
6,181 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (954)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04684472 | Modified CD19 CAR-T in Patients With Relapsed or Refractory CD19+ B-cell Malignancies | unknown | Phase 1 | 18 | Liqun ZouOTHER | 1 | Sep 26, 2022 | clinicaltrials |
| NCT05549284 | Orelabrutinib,Rituximab and Methotrexate in Newly-diagnosed Primary Central Nervous System Lymphoma(PCNSL)(RMO) | unknown | Phase 2 | 36 | Affiliated Hospital to Academy of Military Medical SciencesOTHER | 1 | Sep 22, 2022 |
| clinicaltrials |
| NCT05549973 | Anlotinib Hydrochloride Capsule Monotherapy and Combination Therapy Relapsed and Refractory Multiple Myeloma | unknown | Phase 1 | 32 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Sep 22, 2022 | clinicaltrials |
| NCT05548686 | Benefits of Adapted Physical Activity for Chronic Osteoarticular Pain in Patients With Multiple Myeloma(ALGOMYELOMOV) | unknown | N/A | 15 | University Hospital, CaenOTHER | 0 | Sep 21, 2022 | clinicaltrials |
| NCT03891355 | Carfilzomib + Lenalidomide and Dexamethasone for BTK Inhibitors Relapsed-refractory or Intolerant MCL(FIL_KLIMT) | unknown | Phase 2 | 16 | Fondazione Italiana Linfomi - ETSOTHER | 1 | Sep 15, 2022 | clinicaltrials |
| NCT05536700 | Using Mass Spectrometry (EasyM) Detecting Minimal Residual Disease (MRD) in Multiple Myeloma | unknown | — | 67 | Institute of Hematology & Blood Diseases Hospital, ChinaOTHER | 1 | Sep 13, 2022 | clinicaltrials |
| NCT04277845 | Randomized Phase II Study in Elderly Patients With Newly Diagnosed Multiple Myeloma(KMM1910) | unknown | Phase 2 | 49 | Samsung Medical CenterOTHER | 1 | Sep 9, 2022 | clinicaltrials |
| NCT04688853 | A Study to Investigate the Safety and Efficacy of TEG002 in Relapsed/Refractory Multiple Myeloma Patients | unknown | Phase 1 | 26 | Gadeta B.V.INDUSTRY | 1 | Sep 8, 2022 | clinicaltrials |
| NCT05532761 | Multidimensional Assessment of Quality of Life, Social and Professional Life and Care Utilization in Patients With Diffuse Large Cell B-cell Lymphoma Treated With CAR-T Cells(QUALITOP CAR-T) | unknown | — | 30 | Hospices Civils de LyonOTHER | 1 | Sep 8, 2022 | clinicaltrials |
| NCT03336073 | Carfilzomib, Cyclophosphamide, Dexamethasone in Multiple Myeloma | unknown | Phase 2 | 199 | PETHEMA FoundationOTHER | 1 | Sep 7, 2022 | clinicaltrials |
| NCT05528887 | Study of CAR-T Cell Therapy in the Treatment of Relapsed/Refractory Hematological Malignancies | unknown | Phase 1 | 10 | The Affiliated People's Hospital of Ningbo UniversityOTHER_GOV | 1 | Sep 6, 2022 | clinicaltrials |
| NCT05189782 | Mechanism of Resistance to GNC-038 in Relapsed and Refractory Diffuse Large B-cell Lymphoma | unknown | — | 15 | Ruijin HospitalOTHER | 1 | Aug 31, 2022 | clinicaltrials |
| NCT05509374 | Phase II Study of Carfilzomib, Pomalidomide, and Dexamethasone for Myeloma Patients Who Had Relapsed or Progressed After Carfilzomib, Lenalidomide, and Dexamethasone(KMM2002) | unknown | Phase 2 | 33 | Samsung Medical CenterOTHER | 1 | Aug 22, 2022 | clinicaltrials |
| NCT05509530 | Safety and Efficacy of Anti-BCMA/GPRC5D CAR-T Cell Therapy in Treating Relapsed and Refractory Multiple Myeloma(rr/MM) | unknown | Phase 2 | 30 | Xuzhou Medical UniversityOTHER | 1 | Aug 22, 2022 | clinicaltrials |
| NCT05498636 | SPEL as Introductive Treatment Following Immune-chemotherapy as Consolidated Therapy for R/R DLBCL With p53 and/or c-Myc Expression | unknown | Phase 1 / Phase 2 | 67 | The Affiliated Hospital of Qingdao UniversityOTHER | 1 | Aug 19, 2022 | clinicaltrials |
| NCT05504603 | Zanubrutinib-rituximab(ZR) in Patients With Newly Diagnosed Untreated Mantle Cell Lymphoma | unknown | Phase 2 | 20 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Aug 17, 2022 | clinicaltrials |
| NCT05497102 | Carfilzomib, Lenalidomide, and Dexamethasone Re-induction Followed by the 2nd ASCT in Multiple Myeloma Patients Relapsed After the 1st ASCT(KMM1911) | unknown | Phase 2 | 58 | Samsung Medical CenterOTHER | 1 | Aug 12, 2022 | clinicaltrials |
| NCT05495620 | Long-term KRd in Relapsed and/or Refractory Multiple Myeloma | unknown | — | 300 | Dong-A University HospitalOTHER | 0 | Aug 10, 2022 | clinicaltrials |
| NCT04226937 | DLBCL Interim Response Evaluation for Customised Therapy(DIRECT) | unknown | — | 150 | Cambridge University Hospitals NHS Foundation TrustOTHER | 1 | Aug 5, 2022 | clinicaltrials |
| NCT01374412 | Investigation of Bone Defects and Microcirculation With Computed Tomography and Magnetic Resonance Imaging | unknown | — | 144 | German Cancer Research CenterOTHER | 1 | Aug 4, 2022 | clinicaltrials |
| NCT04935580 | Study of FasT CAR-T GC012F Injection in High Risk TE NDMM Patients | unknown | Phase 1 / Phase 2 | 20 | Shanghai Changzheng HospitalOTHER | 1 | Aug 3, 2022 | clinicaltrials |
| NCT05486013 | Zanubrutinib in the Treatment of Recurrent Refractory Mantle Cell Lymphoma | unknown | — | 30 | Peking University Third HospitalOTHER | 1 | Aug 3, 2022 | clinicaltrials |
| NCT05478343 | Clinical Trial to Evaluate the Safety and Efficacy of IM21 CAR-T Cells in Patients With Relapsed and Refractory (R/R) Multiple Myeloma | unknown | Early Phase 1 | 10 | Beijing Immunochina Medical Science & Technology Co., Ltd.INDUSTRY | 1 | Jul 28, 2022 | clinicaltrials |
| NCT05412329 | Study of Dual Targeted CD19/BCMA FASTCART GC012F in Relapsed/ Refractory Multiple Myeloma | unknown | Phase 1 | 9 | Shanghai Changzheng HospitalOTHER | 1 | Jul 26, 2022 | clinicaltrials |
| NCT03736616 | Acalabrutinib Plus RICE for Relapsed/Refractory DLBCL | unknown | Phase 2 | 47 | Swedish Medical CenterOTHER | 1 | Jul 22, 2022 | clinicaltrials |
| NCT05453669 | Clinical Study of the Efficacy of CD19-CAR-DNT Cells in the Treatment of Relapsed/Refractory B-cell NHL | unknown | Phase 1 | 12 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 12, 2022 | clinicaltrials |
| NCT05444322 | A Study of RD14-01 in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphoma | unknown | Early Phase 1 | 18 | He HuangOTHER | 1 | Jul 11, 2022 | clinicaltrials |
| NCT05381506 | Study of Orelabrutinib in Combination With Gemox in Refractory / Relapsed Diffuse Large B-cell Lymphoma(O-Gemox) | unknown | Phase 2 | 77 | Sun Yat-sen UniversityOTHER | 1 | Jul 8, 2022 | clinicaltrials |
| NCT05448404 | A Head-to-head Comparative Study of 18F-PSMA-1007 PET/CT and 18F-FDG PET/CT Imaging in Multiple Myeloma | unknown | N/A | 30 | First Hospital of China Medical UniversityOTHER | 1 | Jul 8, 2022 | clinicaltrials |
| NCT04845139 | A Case Study of Nivolumab for Relapsed/Refractory Primary Central Nervous System Lymphoma | unknown | N/A | 1 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jul 7, 2022 | clinicaltrials |
| NCT05436223 | Human CD19 Targeted T Cells Injection(CD19 CAR-T) Therapy for Relapsed and Refractory B-cell Non-Hodgkin's Lymphoma | unknown | Phase 2 | 100 | Hrain Biotechnology Co., Ltd.INDUSTRY | 1 | Jul 5, 2022 | clinicaltrials |
| NCT05439538 | Serum NGAL IN Patients With Multiple Myeloma | unknown | — | 60 | Assiut UniversityOTHER | 0 | Jun 30, 2022 | clinicaltrials |
| NCT05430945 | A Study of BCMA-targeted CAR-T Cells Therapy for Refractory/Relapsed Multiple Myeloma | unknown | Early Phase 1 | 100 | Zhejiang UniversityOTHER | 1 | Jun 24, 2022 | clinicaltrials |
| NCT05428670 | The Efficacy and Safety of ZR2 Versus R-CHOP-like Regimen for Elderly Patients With Newly Diagnosed Diffuse Large B Cell Lymphoma. | unknown | Phase 2 | 150 | First Affiliated Hospital of Wenzhou Medical UniversityOTHER | 1 | Jun 23, 2022 | clinicaltrials |
| NCT05429918 | Ibrutinib Combined With R-CHOP/R-DHAP in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged ≤65 Years | unknown | — | 60 | Peking University Third HospitalOTHER | 1 | Jun 23, 2022 | clinicaltrials |
| NCT05425654 | RL-MPV Followed by BBC HCT Using Autologous Stem Cells and Maintenance Therapy With Nivolumab for Newly Diagnosed PCNSL | unknown | Phase 2 | 30 | National Research Center for Hematology, RussiaNETWORK | 1 | Jun 21, 2022 | clinicaltrials |
| NCT05414162 | Multiparametric Cardiac MRI in Patients Under CAR T-cell Therapy | unknown | — | 60 | University Hospital, BonnOTHER | 1 | Jun 15, 2022 | clinicaltrials |
| NCT05406154 | Ibrutinib Combined With Bendamustine and Rituximab in Newly Diagnosed Mantle Cell Lymphoma Patients Who Aged > 65 Years | unknown | — | 60 | Peking University Third HospitalOTHER | 1 | Jun 6, 2022 | clinicaltrials |
| NCT04831658 | A Prospective Clinical Study of BTK Inhibitor, PD-1 and Formustine in the First-line Treatment of Primary Central Nervous System Lymphoma | unknown | Phase 1 / Phase 2 | 40 | Mingzhi ZhangOTHER | 1 | Jun 2, 2022 | clinicaltrials |
| NCT05390749 | Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL | unknown | Phase 2 | 50 | Peking Union Medical College HospitalOTHER | 1 | May 25, 2022 | clinicaltrials |
| NCT05381077 | Evaluation of Whole Body Examination by MRI Integrating the "Zero Time Eco" Sequence (ZTE, Pseudo-CT) for the Detection of Bone Lesions in Multiple Myeloma: Comparison With Pet / CT and Whole Body Scanner(MM-ZTE) | unknown | N/A | 30 | Cliniques universitaires Saint-Luc- Université Catholique de LouvainOTHER | 1 | May 19, 2022 | clinicaltrials |
| NCT03971305 | A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With Systemic ALK(+) ALCL | unknown | — | 300 | Sun Yat-sen UniversityOTHER | 1 | May 9, 2022 | clinicaltrials |
| NCT05364177 | 68Ga-pentixather and 68Ga-pentixafor PET/CT in Multiple Myeloma | unknown | Early Phase 1 | 100 | Peking Union Medical College HospitalOTHER | 1 | May 6, 2022 | clinicaltrials |
| NCT05154474 | Assessment of Sarcopenia at Diagnosis for Patients With Previously Untreated Metastatic Cancer or Hematologic Malignancy(SPACE2) | unknown | — | 150 | WepromOTHER | 1 | May 3, 2022 | clinicaltrials |
| NCT04678089 | Evaluation of Clinical Treatment of Multiple Myeloma Based on Multi-omics | unknown | — | 350 | Beijing Chao Yang HospitalOTHER | 1 | Apr 28, 2022 | clinicaltrials |
| NCT05277493 | A Registry of Chinese AL Amyloidosis Patients Treated With Subcutaneous or Intravenous Daratumumab | unknown | — | 500 | Peking Union Medical College HospitalOTHER | 1 | Apr 27, 2022 | clinicaltrials |
| NCT05334238 | Orelabrutinib Maintenance Therapy After ASCT in Primary Central Nervous System Lymphoma | unknown | Phase 3 | 174 | Ruijin HospitalOTHER | 1 | Apr 19, 2022 | clinicaltrials |
| NCT05331313 | The Aim is to Identify Recurrent Genomic Mutations and/or Predisposing Polymorphisms in Patients With Sporadic Cases of Multiple Myeloma(MMSPORADGEN) | unknown | — | 1,000 | Hospices Civils de LyonOTHER | 1 | Apr 15, 2022 | clinicaltrials |
Data updated 23 days agoSource updated Sep 26, 2022source: clinicaltrials