Subtype
Anorectal Neoplasm
CI-CAN-00001814Explore in graph →
Non-malignant504 active trials1 approved drugs6 evidence items
- NCIt
- C215222
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Subtype
CI-CAN-00001814Explore in graph →
Clinical trials
2,046 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00003652 | Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | completed | Phase 3 | 350 | UNICANCEROTHER | 1 | Feb 17, 2021 | clinicaltrials |
| NCT02526953 | Efficacy Study of Chemoradiotherapy With or Without Paclitaxel in Squamous-cell Anal Carcinoma Patients | unknown | Phase 3 | 314 | Blokhin's Russian Cancer Research CenterOTHER | 0 | Feb 9, 2021 | clinicaltrials |
| NCT04103697 | Neoadjuvant Chemotherapy in Patients With Intermediate Risk Upper and Mid Rectal Cancer(RuCorT-01) | unknown | Phase 3 | 560 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT04134897 | Neoadjuvant Chemotherapy in Patients With Moderate Risk Mid Rectal Cancer(RuCorT-02) | unknown | Phase 3 | 316 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT04135313 | Induction and Consolidation Chemotherapy in Patients With Locally Advanced CRM-positive Rectal Cancer(RuCorT-03) | unknown | Phase 3 | 540 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Feb 9, 2021 | clinicaltrials |
| NCT01224392 | Simultaneous Integrated Boost Preoperative Radiotherapy for Rectum Cancer(RectumSIB) | completed | Phase 3 | 156 | Universitair Ziekenhuis BrusselOTHER | 1 | Dec 30, 2020 | clinicaltrials |
| NCT01500993 | Capecitabine in the Perioperative Treatment of Rectal Cancer(Rektum-III) | completed | Phase 3 | 401 | Universitätsmedizin MannheimOTHER | 1 | Nov 27, 2020 | clinicaltrials |
| NCT04642924 | SGM-101 in Locally Advanced and Recurrent Rectal Cancer(SGM-LARRC) | unknown | Phase 2 / Phase 3 | 203 | Leiden University Medical CenterOTHER | 1 | Nov 24, 2020 | clinicaltrials |
| NCT01164722 | Infrared Coagulator Ablation or Observation in Preventing Anal Cancer in HIV-Positive Patients With Anal Neoplasia | completed | Phase 3 | 120 | AIDS Malignancy ConsortiumNETWORK | 1 | Aug 4, 2020 | clinicaltrials |
| NCT04288999 | Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer(JCOG1801) | recruiting | Phase 3 | 110 | National Cancer Center Hospital EastOTHER | 1 | Jun 4, 2020 | clinicaltrials |
| NCT02371304 | Rectal Preserving Treatment for Early Rectal Cancer. A Multi-centred Randomised Trial of Radical Surgery Versus Adjuvant Chemoradiotherapy After Local Excision for Early Rectal Cancers(TESAR) | unknown | Phase 3 | 302 | Amsterdam UMC, location VUmcOTHER | 1 | May 21, 2020 | clinicaltrials |
| NCT00207831 | Trial Testing Ftorafur (UFT) Associated With Neoadjuvant Radiotherapy Versus Radiotherapy Alone in Rectal Adenocarcinoma(UFT RT Phase 3) | terminated | Phase 3 | 219 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 25, 2020 | clinicaltrials |
| NCT00056459 | Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Metastatic Colorectal Cancer. | completed | Phase 3 | 1,168 | NovartisINDUSTRY | 19 | Feb 10, 2020 | clinicaltrials |
| NCT02928692 | Minocycline Attenuate Postoperative Cognitive Dysfunction and Delirium(MAPOCD) | unknown | Phase 3 | 750 | RenJi HospitalOTHER | 1 | Jan 28, 2020 | clinicaltrials |
| NCT02736942 | COLOR III Trial: Transanal vs Laparoscopic TME(COLORIII) | unknown | Phase 3 | 1,104 | Amsterdam UMC, location VUmcOTHER | 1 | Jun 6, 2019 | clinicaltrials |
| NCT03975049 | Triplet Combination or Doublet Regimen Versus Chemoradiation as Neoadjuvant Therapy for Locally Advanced Rectal Cancer | not yet recruiting | Phase 3 | 933 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Jun 5, 2019 | clinicaltrials |
| NCT03671252 | Prospectively Randomized Control Clinical Trial of FOLFOXIRI Preoperative Chemotherapy Alone on Rectal Cancer in Local Advance Comparing to Oral Capecitabine Combined With Long-term Radiation | recruiting | Phase 3 | 776 | Sun Yat-sen UniversityOTHER | 1 | Jan 23, 2019 | clinicaltrials |
| NCT02751606 | Nano MRI on 7 Tesla in Rectal and Breast Cancer | unknown | Phase 3 | 30 | Radboud University Medical CenterOTHER | 1 | Dec 6, 2018 | clinicaltrials |
| NCT00068692 | Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer | completed | Phase 3 | 225 | National Cancer Institute (NCI)NIH | 1 | Dec 4, 2018 | clinicaltrials |
| NCT01651949 | Multivalent HPV (Human Papillomavirus) Vaccine Study in 16- to 26-Year Old Men and Women (V503-003) | completed | Phase 3 | 2,520 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Nov 27, 2018 | clinicaltrials |
| NCT03415763 | Adjuvant Chemotherapy in Patients With Clinical Stage III Rectal Cancer Undergoing Neoadjuvant Chemoradiotherapy | unknown | Phase 3 | 764 | LI XIN-XIANGOTHER | 1 | Nov 6, 2018 | clinicaltrials |
| NCT00254436 | A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients | terminated | Phase 3 | 50 | M.D. Anderson Cancer CenterOTHER | 1 | Oct 25, 2018 | clinicaltrials |
| NCT02127645 | Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer(NERATEM) | completed | Phase 3 | 25 | European Association for Endoscopic SurgeryOTHER | 1 | Jul 26, 2018 | clinicaltrials |
| NCT03177382 | Total Neoadjuvant Treatment vs. Chemoradiotherapy in Local Advanced Rectal Cancer With High Risk Factors(TNTCRT) | unknown | Phase 3 | 458 | West China HospitalOTHER | 1 | May 8, 2018 | clinicaltrials |
| NCT02907385 | Efficacy and Safety of LifeSeal™ Kit for Colorectal Staple Line Sealing | unknown | Phase 3 | 736 | LifeBond Ltd.INDUSTRY | 7 | Mar 30, 2018 | clinicaltrials |
| NCT00427375 | Local Excision in Downstaged Rectal Cancer(GRECCAR 2) | completed | Phase 3 | 148 | University Hospital, BordeauxOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT03431428 | Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients | unknown | Phase 3 | 477 | Zhang RuiOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT03428529 | Capecitabine Versus Bolus 5-Fu Associated to Radiotherapy as Neoadjuvant Treatment for Rectal Cancer.(INCAGI004) | completed | Phase 2 / Phase 3 | 63 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 0 | Feb 9, 2018 | clinicaltrials |
| NCT02163187 | Sacral Neuromodulation (SNM) With InterStimTM for Bowel Dysfunction Following Surgery for Rectal Cancers With Sphincter Preservation | terminated | Phase 2 / Phase 3 | 4 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 5, 2018 | clinicaltrials |
| NCT00911170 | PAVES: Pegfilgrastim Anti-vascular Endothelial Growth Factor (VEGF) Evaluation Study | completed | Phase 3 | 847 | AmgenINDUSTRY | 17 | Dec 29, 2017 | clinicaltrials |
| NCT02369939 | Effects of Deep Regional Hyperthermia in Patients With Anal Carcinoma Treated by Standard Radiochemotherapy(HYCAN) | unknown | Phase 3 | 118 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 11, 2017 | clinicaltrials |
| NCT03242187 | Trans-anal Versus Laparoscopic TME for Mid and Low Rectal Cancer(MansTaTME) | unknown | Phase 2 / Phase 3 | 30 | Mansoura UniversityOTHER | 1 | Aug 8, 2017 | clinicaltrials |
| NCT00509444 | Cancer Prevention and Treatment Among African American Older Adults: Treatment Trial(CPTD) | completed | Phase 3 | 200 | Johns Hopkins Bloomberg School of Public HealthOTHER | 1 | Apr 20, 2017 | clinicaltrials |
| NCT00056446 | Study of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal Cancer | completed | Phase 3 | 855 | Novartis PharmaceuticalsINDUSTRY | 18 | Mar 6, 2017 | clinicaltrials |
| NCT03038217 | Investigation of the Value of ctDNA in Diagnosis, Treatment, and Surveillance of Surgically Resectable Colorectal Cancer | unknown | Phase 3 | 300 | Peking Union Medical College HospitalOTHER | 0 | Feb 3, 2017 | clinicaltrials |
| NCT01786694 | Feasibility of Microdialysis by Laparoscopy(MTM-COLON-I) | completed | Phase 3 | 11 | Centre Hospitalier Universitaire, AmiensOTHER | 1 | Feb 1, 2017 | clinicaltrials |
| NCT00003596 | Chemotherapy Plus Radiation Therapy in Treating Patients With Stage II or Stage III Anal Cancer | completed | Phase 3 | 682 | Radiation Therapy Oncology GroupNETWORK | 2 | Jan 4, 2017 | clinicaltrials |
| NCT02266849 | Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over Study | terminated | Phase 3 | 12 | Odense University HospitalOTHER | 1 | Oct 11, 2016 | clinicaltrials |
| NCT01372007 | Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma | completed | Phase 3 | 24 | University Hospital, GhentOTHER | 1 | Oct 7, 2016 | clinicaltrials |
| NCT00190541 | Mesorectal Excision (ME) Versus ME With Lateral Node Dissection for Stage II, III Lower Rectal Cancer (JCOG0212) | completed | Phase 3 | 700 | Haruhiko FukudaOTHER | 1 | Sep 22, 2016 | clinicaltrials |
| NCT02905968 | Transanual Tube Placement in Low Anterior Resection (LAR) for Rectal Cancer | unknown | Phase 2 / Phase 3 | 520 | Fudan UniversityOTHER | 1 | Sep 19, 2016 | clinicaltrials |
| NCT00349076 | Neoadjuvant Chemoradiotherapy and Adjuvant Chemotherapy With 5-Fluorouracil and Oxaliplatin Versus 5-Fluorouracil Alone in Rectal Cancer | completed | Phase 3 | 1,256 | University of Erlangen-Nürnberg Medical SchoolOTHER | 1 | Aug 1, 2016 | clinicaltrials |
| NCT02770911 | Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal Cancer | unknown | Phase 3 | 250 | Fujian Medical UniversityOTHER | 0 | May 12, 2016 | clinicaltrials |
| NCT02598414 | The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery | unknown | Phase 2 / Phase 3 | 102 | Acibadem UniversityOTHER | 1 | Nov 24, 2015 | clinicaltrials |
| NCT00075868 | Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer | completed | Phase 3 | 233 | Radiation Therapy Oncology GroupNETWORK | 1 | Nov 17, 2015 | clinicaltrials |
| NCT01211210 | Neoadjuvant FOLFOX6 Chemotherapy With or Without Radiation in Rectal Cancer(FOWARC) | unknown | Phase 2 / Phase 3 | 495 | Sun Yat-sen UniversityOTHER | 1 | May 22, 2015 | clinicaltrials |
| NCT01814969 | Preoperative Hyperfractionated Radiotherapy or Radiochemotherapy in Locally Advanced Rectal Cancer. | unknown | Phase 3 | 260 | Maria Sklodowska-Curie National Research Institute of OncologyOTHER | 1 | May 5, 2015 | clinicaltrials |
| NCT00782457 | Prospective Randomised Study Comparing Laparoscopic Versus Open Surgery in Patients With Rectal Cancer | completed | Phase 3 | 200 | Hospital Universitario Virgen de la ArrixacaOTHER | 0 | Mar 18, 2015 | clinicaltrials |
| NCT01423214 | A Trial to Assess Robot-assisted Surgery and Laparoscopy-assisted Surgery in Patients With Mid or Low Rectal Cancer(COLRAR) | unknown | Phase 3 | 540 | Kyungpook National University HospitalOTHER | 1 | Mar 11, 2015 | clinicaltrials |
| NCT01941979 | A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment. | unknown | Phase 3 | 309 | Instituto do Cancer do Estado de São PauloOTHER | 1 | Oct 30, 2014 | clinicaltrials |
Data updated 23 days agoSource updated Feb 17, 2021source: clinicaltrials