Subtype
Anorectal Neoplasm
CI-CAN-00001814Explore in graph →
Non-malignant504 active trials1 approved drugs6 evidence items
- NCIt
- C215222
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Subtype
CI-CAN-00001814Explore in graph →
Clinical trials
2,046 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03053544 | Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer | completed | Phase 2 | 15 | Sunnybrook Health Sciences CentreOTHER | 1 | Sep 27, 2019 | clinicaltrials |
| NCT01802320 | Akt Inhibitor MK2206 in Treating Patients With Previously Treated Colon or Rectal Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery | completed | Phase 2 | 18 | National Cancer Institute (NCI)NIH | 1 | Sep 20, 2019 |
| clinicaltrials |
| NCT01111604 | A Study of Ramucirumab or Icrucumab in Colorectal Cancer | completed | Phase 2 | 158 | Eli Lilly and CompanyINDUSTRY | 2 | Aug 6, 2019 | clinicaltrials |
| NCT02973672 | Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas | completed | Phase 1 / Phase 2 | 75 | SurgimabINDUSTRY | 1 | Jul 18, 2019 | clinicaltrials |
| NCT00828672 | Neoadjuvant Bevacizumab, Capecitabine and Radiation Therapy With or Without Oxaliplatin Locally Advanced Rectal Cancer(AXEBEAM) | completed | Phase 2 | 84 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Jul 10, 2019 | clinicaltrials |
| NCT01985763 | Genistein in Treatment of Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 13 | Sofya PintovaOTHER | 1 | May 10, 2019 | clinicaltrials |
| NCT01206530 | FOLFOX/Bevacizumab/Hydroxychloroquine (HCQ) in Colorectal Cancer | completed | Phase 1 / Phase 2 | 50 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Apr 18, 2019 | clinicaltrials |
| NCT00645710 | Hepatic Arterial Infusion of Floxuridine, Gemcitabine Hydrochloride, and Radiolabeled Monoclonal Antibody Therapy in Treating Liver Metastases in Patients With Metastatic Colorectal Cancer Previously Treated With Surgery | completed | Phase 1 / Phase 2 | 16 | City of Hope Medical CenterOTHER | 1 | Mar 28, 2019 | clinicaltrials |
| NCT00321685 | Bevacizumab, Radiation Therapy, and Combination Chemotherapy in Treating Patients Who Are Undergoing Surgery for Locally Advanced Nonmetastatic Rectal Cancer | completed | Phase 2 | 57 | National Cancer Institute (NCI)NIH | 1 | Mar 27, 2019 | clinicaltrials |
| NCT01717391 | [F-18] Fluorothymidine PET/CT Imaging for Pelvic Cancers | completed | Phase 2 | 36 | John M. BuattiOTHER | 1 | Mar 26, 2019 | clinicaltrials |
| NCT00409994 | Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer | completed | Phase 1 / Phase 2 | 44 | Maastricht Radiation OncologyOTHER | 1 | Mar 18, 2019 | clinicaltrials |
| NCT00423293 | Intensity-Modulated Radiation Therapy, Fluorouracil, and Mitomycin C in Treating Patients With Invasive Anal Cancer | completed | Phase 2 | 63 | Radiation Therapy Oncology GroupNETWORK | 2 | Feb 27, 2019 | clinicaltrials |
| NCT00257322 | Cellular Immune Augmentation in Colon and Rectal Cancer | completed | Phase 2 | 20 | University of California, IrvineOTHER | 1 | Oct 31, 2018 | clinicaltrials |
| NCT00094809 | Chemotherapy Administered Every 2 Weeks With or Without Pegfilgrastim in Subjects With Advanced or Metastatic Colon Cancer | completed | Phase 2 | 252 | AmgenINDUSTRY | 0 | Oct 17, 2018 | clinicaltrials |
| NCT00418938 | SPIRITT - Second-Line Panitumumab Irinotecan Treatment Trial | completed | Phase 2 | 266 | AmgenINDUSTRY | 0 | Oct 17, 2018 | clinicaltrials |
| NCT01285778 | Vectibix for the Treatment of Anal Cancer(VITAL) | completed | Phase 2 | 58 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 1 | May 16, 2018 | clinicaltrials |
| NCT01923116 | Therapeutic HPV-16 Vaccination for the Treatment of Anal Dysplasia(VACCAIN-T) | completed | Phase 1 / Phase 2 | 40 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Mar 15, 2018 | clinicaltrials |
| NCT03085992 | Folfoxiri Plus Bevacizumab Followed by Chemoradiotherapy Plus Bevacizumab in Patients With Resectable Rectal Cancer(TRUST) | completed | Phase 2 | 49 | Azienda Ospedaliero, Universitaria PisanaOTHER | 1 | Mar 14, 2018 | clinicaltrials |
| NCT01585428 | Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated Cancers | completed | Phase 2 | 29 | National Cancer Institute (NCI)NIH | 1 | Mar 7, 2018 | clinicaltrials |
| NCT02353858 | Preoperative Radiochemotherapy With Hyperthermia for Locally Advanced Rectal Cancer(HT01) | completed | Phase 2 | 78 | University Hospital TuebingenOTHER | 1 | Feb 13, 2018 | clinicaltrials |
| NCT01589471 | The Value of Botox-A for Management of Low Anterior Resection Syndrome | completed | Phase 2 | 23 | Centre hospitalier de l'Université de Montréal (CHUM)OTHER | 1 | Feb 12, 2018 | clinicaltrials |
| NCT03428529 | Capecitabine Versus Bolus 5-Fu Associated to Radiotherapy as Neoadjuvant Treatment for Rectal Cancer.(INCAGI004) | completed | Phase 2 / Phase 3 | 63 | Instituto Nacional de Cancer, BrazilOTHER_GOV | 0 | Feb 9, 2018 | clinicaltrials |
| NCT00972881 | Capecitabine, Irinotecan Hydrochloride, Cetuximab, and Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal Cancer(EXCITE) | completed | Phase 1 / Phase 2 | 82 | University College, LondonOTHER | 1 | Oct 25, 2017 | clinicaltrials |
| NCT00682786 | Genotype-directed Neoadjuvant Chemoradiation for Rectal Carcinoma | completed | Phase 2 | 135 | Washington University School of MedicineOTHER | 1 | Oct 6, 2017 | clinicaltrials |
| NCT02280811 | T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated Cancers | completed | Phase 1 / Phase 2 | 12 | National Cancer Institute (NCI)NIH | 1 | Sep 6, 2017 | clinicaltrials |
| NCT00847119 | Xeloda and Bevacizumab to Treat Rectal Cancer(xeberecto) | completed | Phase 2 | 43 | Institut Català d'OncologiaOTHER | 1 | Aug 29, 2017 | clinicaltrials |
| NCT01333709 | Multicenter Phase 2 Trial: a Tailored Strategy for Locally Advanced Rectal Carcinoma(GRECCAR4) | completed | Phase 2 | 150 | Institut du Cancer de Montpellier - Val d'AurelleOTHER | 1 | Aug 21, 2017 | clinicaltrials |
| NCT00865189 | A Study of Bevacizumab (Avastin) in Participants With Newly Diagnosed Locally Advanced Rectal Cancer(INOVA) | completed | Phase 2 | 91 | Hoffmann-La RocheINDUSTRY | 1 | Aug 4, 2017 | clinicaltrials |
| NCT01013805 | Preoperative Radiotherapy and Chemotherapy in Patients With Locally Advanced Rectal Cancer(PROArCT) | completed | Phase 2 | 41 | Trans Tasman Radiation Oncology GroupOTHER | 1 | Jul 12, 2017 | clinicaltrials |
| NCT01807546 | Oral Rigosertib for Squamous Cell Carcinoma | completed | Phase 2 | 64 | Traws Pharma, Inc.INDUSTRY | 1 | Jun 26, 2017 | clinicaltrials |
| NCT00468910 | Aspirin in Preventing Colorectal Cancer in Patients at Increased Risk of Colorectal Cancer | completed | Phase 2 | 79 | National Cancer Institute (NCI)NIH | 1 | May 31, 2017 | clinicaltrials |
| NCT00307736 | Bevacizumab, Erlotinib and 5-Fluorouracil With External Beam Radiation Therapy in Locally Advanced Rectal Cancer | completed | Phase 1 / Phase 2 | 32 | Massachusetts General HospitalOTHER | 1 | May 10, 2017 | clinicaltrials |
| NCT01273051 | Transanal Endoscopic Microsurgery (TEM) After Radiochemotherapy for Rectal Cancer(CARTS) | completed | Phase 2 | 55 | Radboud University Medical CenterOTHER | 1 | Apr 14, 2017 | clinicaltrials |
| NCT01060007 | Five Fractions of Radiotherapy Followed by Full Dose FOLFOX Chemotherapy as Preoperative Treatment for Rectal Cancer | completed | Phase 2 | 80 | Washington University School of MedicineOTHER | 1 | Mar 8, 2017 | clinicaltrials |
| NCT02526134 | Placing Trust in Endoscopic Ultrasonography: Impact on Planning Conformal Radiotherapy of Cancer of the Esophagus and Rectum(FIDUCOR) | completed | Phase 2 | 29 | Institut Paoli-CalmettesOTHER | 1 | Mar 3, 2017 | clinicaltrials |
| NCT00335504 | Atorvastatin Calcium, Oligofructose-Enriched Inulin, or Sulindac in Preventing Cancer in Patients at Increased Risk of Developing Colorectal Neoplasia | completed | Phase 2 | 85 | National Cancer Institute (NCI)NIH | 1 | Feb 15, 2017 | clinicaltrials |
| NCT01749956 | 5-FU, Aflibercept, and Radiation (RT) for Preoperative and Postoperative Patients With Stage II/III Rectal Cancer | completed | Phase 2 | 39 | SCRI Development Innovations, LLCOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT01507103 | Tecemotide (L-BLP25) in Rectal Cancer(SPRINT) | completed | Phase 2 | 124 | Merck KGaA, Darmstadt, GermanyINDUSTRY | 1 | Jan 13, 2017 | clinicaltrials |
| NCT02694718 | A Study of Capecitabine Plus Oxaliplatin in Combination With Pre-operative Pelvic Radiotherapy in Rectal Cancer | completed | Phase 2 | 60 | Hoffmann-La RocheINDUSTRY | 1 | Jan 11, 2017 | clinicaltrials |
| NCT02236884 | The Feasibility and Safety of No-scar Transanal Total Mesorectal Excision for Rectal Cancer | completed | Phase 1 / Phase 2 | 20 | Sun Yat-sen UniversityOTHER | 1 | Dec 19, 2016 | clinicaltrials |
| NCT00527111 | Pre-op Rectal ChemoRad +/- Cetuximab | completed | Phase 2 | 139 | US Oncology ResearchINDUSTRY | 1 | Nov 3, 2016 | clinicaltrials |
| NCT01043484 | Safety and Efficacy Study to Compare Capecitabine + Bevacizumab Versus Capecitabine, Concomitantly With Radiotherapy as Neoadjuvant Treatment for Patients With Localized and Resectable Rectal Cancer(AVAXEL) | completed | Phase 2 | 90 | Spanish Cooperative Group for the Treatment of Digestive Tumours (TTD)OTHER | 1 | Oct 19, 2016 | clinicaltrials |
| NCT00278694 | Oxaliplatin and 5-FU Based Preoperative Chemoradiation(LARC-RRP) | completed | Phase 2 | 109 | Oslo University HospitalOTHER | 1 | Sep 29, 2016 | clinicaltrials |
| NCT01269229 | A Trial of Neoadjuvant FOLFOX6 With Short Course Radiotherapy in Patients With Unresectable Rectal Cancer and Liver Metastasis | completed | Phase 2 | 32 | Yonsei UniversityOTHER | 1 | Sep 7, 2016 | clinicaltrials |
| NCT00336856 | Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy | completed | Phase 2 | 35 | University of PittsburghOTHER | 1 | Jul 12, 2016 | clinicaltrials |
| NCT00931203 | Trial of Celecoxib With Preoperative Chemo- Radiation for Locally Advanced Rectal Cancer | completed | Phase 2 | 55 | National Health Research Institutes, TaiwanOTHER | 1 | May 4, 2016 | clinicaltrials |
| NCT02745639 | Preoperative Chemoradiation With VMAT-SIB in Rectal Cancer(GRACE) | completed | Phase 2 | 18 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 0 | Apr 20, 2016 | clinicaltrials |
| NCT02723253 | Concurrent Chemoradiation With Concomitant Boost In Locally Advanced Rectal Cancer | completed | Phase 2 | 18 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 0 | Mar 30, 2016 | clinicaltrials |
| NCT01821105 | 2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer | completed | Phase 2 | 21 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Mar 2, 2016 | clinicaltrials |
| NCT00587964 | Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases | completed | Phase 2 | 51 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Feb 22, 2016 | clinicaltrials |
Data updated 23 days agoSource updated Sep 27, 2019source: clinicaltrials