Angiocentric Glioma — Variants & evidence

Angiocentric Glioma — Variants & evidence · CancerIndex

Variants & evidence

Curated clinical evidence by variant and therapy

5 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.

civicCuratedShowing 1–5 of 5 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
QKI Fusion3
(diagnostic)	Diagnostic	B	Supports Positive	4	accepted	EID11065 A comprehensive genomic analysis was conducted on 172 cases of pediatric low-grade gliomas (PLGGs) across various histologic subtypes, utilizing whole-genome sequencing (WGS) and/or RNA sequencing. Th… (full text at CIViC) PMID 26829751 · Bandopadhayay et al., 2016 · Open in CIViC	civic
〃	Diagnostic	B	Supports Positive	4	accepted	EID11773 The study compiled clinicopathologic and molecular features of 46 gliomas with a MYB or MYBL1 alteration diagnosed at a single center. The tumors showed low-grade histopathologic features and were bro… (full text at CIViC) PMID 31595312 · Chiang et al., 2019 · Open in CIViC	civic
〃	Diagnostic	B	Supports Positive	3	accepted	EID11769 Comprehensive molecular studies through whole genome, whole exome, transcriptome sequencing, genome-wide copy number analysis, clustering analysis by DNA methylation profiling, as well as mutation hot… (full text at CIViC) PMID 26810070 · Qaddoumi et al., 2016 · Open in CIViC	civic
MYB Rearrangement1
(diagnostic)	Diagnostic	C	Supports Positive	2	accepted	EID11774 Copy-number analysis was performed on 44 diffuse pediatric low-grade gliomas (PLGGs) to identify recurrent alterations. The most significant event, focal 8q13.1 gain, was observed in 28% (5/18) of dif… (full text at CIViC) PMID 23633565 · Ramkissoon et al., 2013 · Open in CIViC	civic
MYB Truncation1
(diagnostic)	Diagnostic	C	Supports Positive	2	accepted	EID11775 A research study performed in 2010 involved 57 pediatric low-grade gliomas (LGGs) and a comparison group of 59 pediatric high-grade gliomas (HGGs). Among the LGG group, there were 34 cases of pilocyti… (full text at CIViC) PMID 21046410 · Tatevossian et al., 2010 · Open in CIViC	civic

Data updated 12 hours agoSource updated unknownsource: civic (CC0)

Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.