Hematologic Malignancy
AL Amyloidosis
CI-CAN-00008703Explore in graph →
HematologicNon-malignant31 active trials
- NCIt
- C158963
- MeSH
- D000075363
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Hematologic Malignancy
CI-CAN-00008703Explore in graph →
Clinical trials
79 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05184088 | Efficacy of [18F]Florbetaben PET for Diagnosis of Cardiac AL Amyloidosis(CArdiag) | completed | Phase 3 | 244 | Lantheus Germany GmbHINDUSTRY | 4 | Aug 3, 2026 | clinicaltrials |
| NCT04617925 | A Study of Belantamab Mafodotin in Patients With Relapsed or Refractory AL Amyloidosis(EMN27) | completed | Phase 2 | 35 | Stichting European Myeloma NetworkNETWORK | 6 | Jul 31, 2026 |
| clinicaltrials |
| NCT07585331 | Towards Effective, Patient-tailored Anti-plasma Cell Therapies in AL Amyloidosis: Predicting Drug Response and Overcoming Drug Resistance | completed | — | 250 | Fondazione IRCCS Policlinico San Matteo di PaviaOTHER | 1 | May 13, 2026 | clinicaltrials |
| NCT04392960 | Novel Imaging Tools in Newly-diagnosed Patients With Cardiac AL Amyloidosis | completed | N/A | 30 | Fondazione IRCCS Policlinico San Matteo di PaviaOTHER | 1 | Apr 16, 2026 | clinicaltrials |
| NCT03431896 | Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis(MED-hATTR) | completed | — | 37 | The Cleveland ClinicOTHER | 1 | Mar 12, 2026 | clinicaltrials |
| NCT01758042 | Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders(BMT) | completed | N/A | 10 | Massachusetts General HospitalOTHER | 1 | Mar 6, 2026 | clinicaltrials |
| NCT04304144 | A Study to Evaluate the Safety and Tolerability of CAEL-101 in Patients With AL Amyloidosis | completed | Phase 2 | 25 | Alexion Pharmaceuticals, Inc.INDUSTRY | 1 | Mar 5, 2025 | clinicaltrials |
| NCT02245867 | Study of Chimeric Fibril-Reactive Monoclonal Antibody 11-1F4 in Patients With AL Amyloidosis | completed | Phase 1 | 30 | Alexion Pharmaceuticals, Inc.INDUSTRY | 1 | Feb 7, 2025 | clinicaltrials |
| NCT05199337 | Phase 1/2 Study of ZN-d5 for the Treatment of Relapsed or Refractory Light Chain (AL) Amyloidosis | completed | Phase 1 / Phase 2 | 18 | K-Group Alpha, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc.INDUSTRY | 7 | Sep 19, 2024 | clinicaltrials |
| NCT05028374 | COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies | completed | Phase 2 | 119 | Barbara Ann Karmanos Cancer InstituteOTHER | 1 | Dec 20, 2023 | clinicaltrials |
| NCT03236792 | Ixazomib In Combination With Cyclophosphamide And Dexamethasone for Newly Diagnosed AL Amyloidosis | completed | Phase 1 / Phase 2 | 28 | Icahn School of Medicine at Mount SinaiOTHER | 1 | Sep 29, 2022 | clinicaltrials |
| NCT04937777 | A Study on the Management and Outcome of Patients With Systemic AL Amyloidosis in Europe | completed | — | 4,481 | European Myeloma Network B.V.NETWORK | 10 | Sep 27, 2022 | clinicaltrials |
| NCT02841033 | Daratumumab for the Treatment of Patients With AL Amyloidosis | completed | Phase 1 / Phase 2 | 22 | Boston Medical CenterOTHER | 1 | May 7, 2021 | clinicaltrials |
| NCT01570387 | A Phase I/II Trial of Pomalidomide and Dexamethasone in Subjects With Previously-Treated AL Amyloidosis | completed | Phase 1 / Phase 2 | 27 | Boston Medical CenterOTHER | 1 | Sep 22, 2020 | clinicaltrials |
| NCT01222260 | Bendamustine and Dexamethasone in Patients With Relapsed AL Amyloidosis | completed | Phase 2 | 40 | Columbia UniversityOTHER | 1 | Mar 30, 2020 | clinicaltrials |
| NCT02574676 | Quality of Life (QOL) Registry for Patients With AL Amyloidosis | completed | — | 343 | Prothena Biosciences Ltd.INDUSTRY | 1 | Apr 9, 2019 | clinicaltrials |
| NCT02632786 | The PRONTO Study, a Global Phase 2b Study of NEOD001 in Previously Treated Subjects With Light Chain (AL) Amyloidosis(PRONTO) | completed | Phase 2 | 129 | Prothena Biosciences Ltd.INDUSTRY | 10 | Apr 5, 2019 | clinicaltrials |
| NCT01277016 | A Trial for Systemic Light-chain (AL) Amyloidosis(EMN-03) | completed | Phase 3 | 110 | European Myeloma Network B.V.NETWORK | 1 | Mar 10, 2017 | clinicaltrials |
| NCT02257905 | Allo SCT in Amyloidosis Non-interventional Study | completed | — | 14 | European Society for Blood and Marrow TransplantationNETWORK | 3 | Jul 24, 2015 | clinicaltrials |
| NCT01815086 | Radioimmunoimaging of Light Chain (AL) Amyloidosis | completed | Phase 1 | 30 | University of TennesseeOTHER | 1 | Sep 18, 2013 | clinicaltrials |
| NCT01409148 | Radioimmunoimaging of AL Amyloidosis | completed | Phase 1 | 38 | University of TennesseeOTHER | 1 | Oct 11, 2012 | clinicaltrials |
Data updated 22 days agoSource updated Aug 3, 2026source: clinicaltrials