VHL T100Nfs*32 (c.298dupA)

CI-VAR-00004253Explore in graph →CIViC 3150

Curated evidence

Evidence by cancer (2 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–2 of 2 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Von Hippel-Lindau Disease2unmapped disease
VHL T100Nfs*32 (c.298dupA)	(predisposing)	Predisposing	B	Supports Predisposition	4	submitted	EID7753 Patients presenting with cerebellar hemangioblastomas (HBs) were prospectively enrolled alongside family members, resulting in 84 patients in 7 families with VHL mutations, and subjected to peripheral… (full text at CIViC) PMID 16572651 · Rasmussen et al., 2006 · Open in CIViC	civic
VHL T100Nfs*32 (c.298dupA)	(predisposing)	Predisposing	B	N/A N/A	4	rejected	EID8630 "Patients presenting with cerebellar hemangioblastomas at the Mexican National institute of Neurology and Neurosurgery to were prospectively enrolled alongside family members, resulting in 84 patients… (full text at CIViC) PMID 16572651 · Rasmussen et al., 2006 · Open in CIViC

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.