VHL S111I (c.332G>T)

CI-VAR-00003981Explore in graph →CIViC 3747

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Malignant Pancreatic Neoplasm1
VHL S111I (c.332G>T)	(predisposing)	Predisposing	C	Supports Predisposition	2	submitted	EID10186 Gene symbol publication providing minimal information. A VHL gene mutation at codon 111, AGC-ATC, Ser-Ile is associated to pancreatic cancer. It is unclear if this variant is somatic or germline. It i… (full text at CIViC) PMID 10942118 · Bradley et al., 2000 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.