VHL N90del (c.268_270del)

CI-VAR-00002975Explore in graph →CIViC 4201

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Von Hippel-Lindau Disease1unmapped disease
VHL N90del (c.268_270del)	(predisposing)	Predisposing	C	Supports Predisposition	3	submitted	EID10707 At 40Y, patient 4 was diagnosed with cerebellar and spinal hemangioblastomas. He had multiple cysts in the kidneys and pancreas, as well as kidney stones, leading to a diagnosis of VHL disease type 1.… (full text at CIViC) PMID 32179488 · Faiyaz-Ul-Haque et al., 2020 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.