VHL I75Yfs*57 (c.224dupT)

CI-VAR-00002022Explore in graph →CIViC 3154

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Von Hippel-Lindau Disease1unmapped disease
VHL I75Yfs*57 (c.224dupT)	(predisposing)	Predisposing	C	N/A N/A	2	rejected	EID8644 Nine patients were recruited who were previously treated for spinal cord hemangioblastomas including five patients with VHL disease. VHL mutation analysis was performed in three patients and two of th… (full text at CIViC) PMID 19096585 · Na et al., 2007 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.