VHL Exon 2-3 Deletion

CI-VAR-00001008Explore in graph →CIViC 1971

Curated evidence

Evidence by cancer (5 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–5 of 5 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Von Hippel-Lindau Disease5unmapped disease
VHL Exon 2-3 Deletion	(predisposing)	Predisposing	C	Supports Predisposition	3	submitted	EID5306 43 Italian patients were molecularly analyzed for Von Hippel-Lindau disease based on clinical suspicion. 1 of the 43 patients was found to have the above mutation. Clinical manifestations associated w… (full text at CIViC) PMID 19464396 · Ciotti et al., 2009 · Open in CIViC	civic
VHL Exon 2-3 Deletion	(predisposing)	Predisposing	C	Supports Uncertain Significance	3	submitted	EID6349 37 Danish patients diagnosed with VHL before 18 years from a prospective cohort study from Denmark's National vHL Research Database (Binderup et al., 2013) were assessed. 2 families each with 1 patien… (full text at CIViC) PMID 28650583 · Launbjerg et al., 2017 · Open in CIViC

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.