TP53 R267P

CI-VAR-00003795Explore in graph →CIViC 1054

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Unmapped disease1unmapped disease
TP53 R267P	(functional)	Functional	D	Supports Loss Of Function	3	submitted	EID13192 In a biopsy sample from a patient with lung squamous cell carcinoma, split FASAY identified TP53 R267P (codon 267 CGG>CCG). The 3′ FASAY fragment containing codon 267 produced 91.8% red colonies, comp… (full text at CIViC) PMID 15161705 · Fouquet et al., 2004 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.