PTEN Y336*

CI-VAR-00004801Explore in graph →CIViC 3405

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Obsolete PTEN Hamartoma Tumor Syndrome1unmapped disease
PTEN Y336*	(predisposing)	Predisposing	C	N/A N/A	2	submitted	EID9471 This retrospective study of 74 familial breast cancers was designed to identify new biomarkers of breast cancer in the background of early PTEN loss. A 48 year old female with invasive apocrine carcin… (full text at CIViC) PMID 20712882 · Banneau et al., 2010 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.