PIK3CA R93Q

CI-VAR-00003932Explore in graph →CIViC 3434

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Unmapped disease1unmapped disease
PIK3CA R93Q	(functional)	Functional	D	Supports Unaltered Function	3	submitted	EID9529 The functional significance of several PIK3CA mutations found in endometrial cancer were assessed by measuring AKT phosphorylation in transfected U2OS cells. PIK3CA R93Q showed levels of AKT activatio… (full text at CIViC) PMID 21266528 · Rudd et al., 2011 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.