Variant · Fusion
PAX5 Fusion
CI-VAR-00001513Explore in graph →CIViC 5425
Curated evidence
Evidence by cancer (3 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 30643249
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| B-lymphoblastic Leukemia With PAX5alt3unmapped disease | ||||||||
| PAX5::v Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 5 | accepted | EID12867This landmark study provided revised classification of B-lymphoblastic leukemia (B-ALL) based on integrated genomic findings from 1,988 childhood and adult B-ALLs. All cases were subjected to RNA-seq … (full text at CIViC) PMID 30643249 · Gu et al., 2019 · Open in CIViC | civic |
| PAX5::v Fusion | (diagnostic) | Diagnostic | B | Supports Positive | 5 | accepted | EID12868This European population-based cohort study examined the genomic landscape of 110 consecutively diagnosed childhood (aged 1-18 years) “B-other” lymphoblastic leukemia (ALL) cases, collected over 7 yea… (full text at CIViC) PMID 30630978 · Zaliova et al., 2019 · Open in CIViC | |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available