Variant · Expression
NR2F2 OVEREXPRESSION
CI-VAR-00003032Explore in graph →CIViC 2419
Curated evidence
Evidence by cancer (1 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26261604
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Malignant Colorectal Neoplasm1 | ||||||||
| NR2F2 OVEREXPRESSION | (prognostic) | Prognostic | B | Supports Poor Outcome | 4 | submitted | EID6461Statistical analysis showed that the inverse relationship between COUP-TF II and SMAD4 expression was shown in 112 different patients with Colorectal Cancer(CRC)(45 COUP-TF II-positive/SMAD4-negative … (full text at CIViC) PMID 26261604 · Wang et al., 2015 · Open in CIViC | civic |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available
No ClinVar interpretation attached to this variant.