MIR218-1 EXPRESSION

CI-VAR-00000940Explore in graph →CIViC 476

Curated evidence

Evidence by cancer (2 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–2 of 2 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Malignant Colorectal Neoplasm2
MIR218-1 EXPRESSION	(prognostic)	Prognostic	B	Supports Better Outcome	3	accepted	EID1119 Researchers examined the prognostic role of miR-218 expression in CRC tumor samples when receiving 5-FU based treatment. CRC samples from patients who received first-line 5-FU-based adjuvant chemother… (full text at CIViC) PMID 26442524 · Li et al., 2015 · Open in CIViC	civic
MIR218-1 EXPRESSION	(prognostic)	Prognostic	B	Supports Better Outcome	3	accepted	EID1120 Researchers examined the overall and progression free survival of CRC patients receiving first line 5-Fluorouracil therapy. Samples were stratified into two groups (low/high expressing miR-218). Kapl… (full text at CIViC) PMID 26442524 · Li et al., 2015 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.