KDR S1100F

CI-VAR-00003976Explore in graph →CIViC 3647

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Malignant Colorectal Neoplasm1
KDR S1100F	(oncogenic)	Oncogenic	D	Supports Oncogenicity	2	submitted	EID9950 The colon cancer cell line COLO-320 was transfected with VEGFR2 (KDR) S1100F mutation. When injected into immune deficient mice, these cells were capable of causing tumor formation reaching the establ… (full text at CIViC) PMID 29588308 · Toledo et al., 2018 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.