IL7R V253G

CI-VAR-00004507Explore in graph →CIViC 2348

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Childhood B-cell Acute Lymphoblastic Leukemia1unmapped disease
IL7R V253G	(diagnostic)	Diagnostic	C	Supports N/A	2	submitted	EID6227 In Roberts et al. (N. Engl. J. Med. 2014) the V253G was found in two cases of Ph-like B-ALL which also had CRLF2 overexpression. PMID 25207766 · Roberts et al., 2014 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.