GATA3 Mutation

CI-VAR-00002733Explore in graph →CIViC 4506

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Histiocytosis-Lymphadenopathy Plus Syndrome1unmapped disease
KRAS G12R AND GATA3 Mutation AND GNAS Mutation	Cobimetinib	Predictive	C	Supports Sensitivity Response	2	submitted	EID11330 This case study is on a 60-year-old man with a 7-year history of fatigue that was noted to have a palpable abdominal mass while being seen for gastroesophageal reflux disease. A CT scan of the abdomen… (full text at CIViC) PMID 29236635 · Jacobsen et al., 2017 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.