ETV6 Mutation

CI-VAR-00002699Explore in graph →CIViC 2567

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Myelodysplastic Syndrome1
ETV6 Mutation	(prognostic)	Prognostic	B	Supports Poor Outcome	4	submitted	EID6946 In a study of 439 patients with myelodysplastic syndrome, patients with ETV6 mutations (N=12) has worse overall survival than wildtype patients (N=427) (P=0.05 univariate). This difference was also ob… (full text at CIViC) PMID 21714648 · Bejar et al., 2011 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.