ZNF880 Fusion

CI-VAR-00001360Explore in graph →CIViC 4447

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
HER2-Positive Breast Carcinoma1
EGFR::ZNF880 Fusion	Pyrotinib	Predictive	C	Supports Sensitivity Response	2	submitted	EID11215 Case report describing a 34-year-old female patient without a family history of breast cancer. After a radical mastectomy, histopathology revealed an invasive ductal carcinoma HER2 positive (FISH). Sh… (full text at CIViC) PMID 33371069 · Yue et al., 2020 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.