Variant · Fusion
FGFR1 e24::e10
CI-VAR-00004944Explore in graph →CIViC 5026
Curated evidence
Evidence by cancer (1 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 29883838
- Run
- ING-CIVIC-20260908-000001
| Molecular profile | Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| Lung Non-Small Cell Carcinoma1 | ||||||||
| EGFR::FGFR1 e24::e10 | (prognostic) | Prognostic | C | Supports Poor Outcome | 1 | submitted | EID11143A single case with EGFR(ex24)::FGFR1(ex10) was identified in a large study of 3505 EGFR(del19, L858R, G719*, S768I, and L851Q)-positive NSCLC cases. The goal of the study was to analyze the role of co… (full text at CIViC) PMID 29883838 · Schrock et al., 2018 · Open in CIViC | civic |
ClinVar
Clinical significance (0)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
Data not yet available
No ClinVar interpretation attached to this variant.