DDR2 S768R

CI-VAR-00004120Explore in graph →ENST00000367922.3:c.2304T>AClinVar 375878 CIViC 145

Curated evidence

Evidence by cancer (1 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

civicCuratedShowing 1–1 of 1 evidence items across 1 cancer context on this page · levels, directions and significance as curated at the source; each row links to its CIViC record.

Molecular profile	Therapy	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
Lung Squamous Cell Carcinoma1
DDR2 S768R	Dasatinib + ErlotinibCombination	Predictive	C	Supports Sensitivity Response	3	accepted	EID272 In a patient expressing a DDR2 S768R mutation, treatment with dasatinib plus erlotinib acheived a partial response. PMID 22328973 · Hammerman et al., 2011 · Open in CIViC	civic

ClinVar

Clinical significance (0)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

Data not yet available

No ClinVar interpretation attached to this variant.