HNF1A NM_000545.8(HNF1A):c.1478T>C (p.Met493Thr)

CI-VAR-00170455Explore in graph →p.Met493ThrNM_000545.8:c.1478T>CClinVar 997653 rs1002380887

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
997653	Uncertain significance/Uncertain risk allele	criteria provided, multiple submitters, no conflicts	2	Nonpapillary renal cell carcinoma; Maturity-onset diabetes of the young	germline	3	Sep 17, 2021	clinvar