PDHB NM_000925.4(PDHB):c.310T>G (p.Leu104Val)

CI-VAR-00169448Explore in graph →p.Leu104ValNM_000925.4:c.310T>GClinVar 978596 rs201199166

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
978596	Likely pathogenic	criteria provided, single submitter	1	Pyruvate dehydrogenase E1-beta deficiency; Uterine corpus endometrial carcinoma; Thyroid cancer, nonmedullary, 1; Acute myeloid leukemia; Familial cancer of breast; Lung cancer	germline	3	Oct 09, 2023	clinvar