Variant · Snv
CDK5RAP2 NM_018249.6(CDK5RAP2):c.1490A>G (p.Asn497Ser)
CI-VAR-00169337Explore in graph →p.Asn497SerNM_018249.6:c.1490A>GClinVar 975516 rs375863465
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 975516 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Intellectual disability; Ovarian serous cystadenocarcinoma; Inborn genetic diseases | germline | 5 | Dec 03, 2025 | clinvar |