Variant · Deletion

ZNF469 NC_000016.10:g.88324127_88331653del

CI-VAR-00169080Explore in graph →ClinVar 974324

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
974324	Pathogenic	no assertion criteria provided	0	Fanconi anemia complementation group A	germline	1	Feb 28, 2020	clinvar

Nomenclature

Record

Gene: ZNF469
Type: Deletion
HGVS g.: NC_000016.10:g.88324127_88331653del
Assembly: GRCh38
Position: chr16:88324126-88331653
Ref / Alt: GTCAGCGCCTCCCCACGGGGCCTGTTCGGGGCTACTTGGGCTTCCTCACAGCATGAGGGCTGGGTCCCAAGAGGCAGGAAGTAGAGGCTGTCAGTTTCGGACCGCCAGCCCTGAAATTTTCTGAGCAATACTTCTGCAGCATTCTGTTTTGGCCAAGAAGTAAAAAGGTCCAGATTCAAAGGCAGAGACGCAGACCCCCACACACACCCCTTATGGGAGGTGGGTGGAAGGATGTGGGGGGCTGTTGTGTCACAGCTGTGCCGTCTGGGATGTTGACCTCCCCAGAGCTCTCAGGTGTGAACACACGTGTGGCCAGGCCTCAGTGCTGTCCTCTCCTATGGCTGTGATGCAGAGAGTCCCAGAACCAGGGCTCAGCCCGGGAGGGTTCTTGGCTTCACTCAGGAAAGAATTTGAAAGCCAGCTGGTGGTGGAAGGCAGGTTTACTTAAGCGGCCGTGTACAGAGAGTTGCTGCTCCTTGCAGAGCAGGGCTAACCCACAGGGAGTGCGCCAGGGTGAGTGCATAAGGGACTGTAGCTGTTTTTATACCCACTTTTAAGTATGTGCGAATTAAGGGGAAGGTTATTCAGAAATCTCTAGAAAGGGGGCGGCACCTTCCAGATGTTGCCATTGCGTTTGTAAACTGTCATGGTGCCGGTGGGTGTGTCTTATGCTGATGGGCAGAGGGGGCAGCTGGAGGAAGCTGTGTTAGTCTGTTCTTGCACTGCTATAGAGAAATACTTGATACTGGGCAATTTATAAAGAAAAGAGGGTTGGCTCACAGTTCTGTAGGCCGTACAGGAAGCATGGTAGCTTCTGCTTCTGGGGAGGCCTCAGGAAACTTACAGTCATGGTGGAAGGTGAAGGGGGATCCAGCACTTCAGCCAGTGGGAGCAGGAGGAAAAGAGAGAGGGAGGAGGTGCCCTTGGGAAATATCCTTCCAGCAGCTTCTGGTTGAGATCACATCCAGCTGCGGCATACTCAGGGTCTCAAGTCCTCACCTGCACACTCCAGGTGGTCCCGACAGCAGCTGCGACATACACAGGGCCTCAAGTCCTCACCTGCACACTCCAGGTGGTCGCGACAGCAGCTGTGACATACACAGGGCCTCAAGTCCTCACCGGCACACTCCAGGTGGTCCCTACAGGCTCCGTAAGCTGCCCGAGGTGCACCCCGGGGGGCCGCAGGGGCTCAGACCCAGGACACCCACCAGACTGCACAATTGGTGGCCAGCTTCTGGGGCAACCATCAGGGTCACAGTGGGAGAGGCACAATTTCCACCCAGAGCATCACTCTTCCCAATTCATGCCTGAAGGCGGGGCAGCCGCTGAGTACCCTGCCCAGGGGACCCGGAGGACACAGGTCAGTGATAGGCGTGGCCCCACCACTGCAGCCAGGGGCACTATGTGTGGTGGCGCCAAGCCCAGCATGGCCAGAAATGACACTGATACCCACACCAGGACACAGTGTCCCAGGGTGGTAGAGCTGGAAGGGCCTCTGCCACTTAGGGCTCCTGGTCCCATCCCTCATGCAATTTGTGGCCTGTGAGACCCCCTAAGGGAAAGTGACTTGTTCAATGTCACCCCAAAAGTCTGCAGTGGGGCCAGGACAGACAGGGCCTTGCCACTCAAATGCTCCGTGTGACGGCTACCCTGGTCCTTCCTTCCCCTCTTTCTCCTTCCTTCCTCCCTTTCCTCCTTCCTTTCTTCCACGCATCCCAGATGGGGCTGCAGGGCAGAAGGATCGGTGCTCTGCCCCCTTAGACCTGAAGGACGCCACTTCCTCTCTAGCCTCAGCTTCCTCAGCTGTACACTGTGAGCAATAGAGCTAACAACACCTGTCAGTCAGTCCAGGGGTGGCCACTGTGCCTGTGATTGCGCCCCCTCCCCACTCCCAGCCAGTGTGATCCTGTAGGCAGAGAGGAGGGGCTGCCAACCCAGAGGCCCCAGCAATGGGCCACAGACATGTCCTGGTCTCAGAGCCTTTGTGATATGGTTTGGCTGTGTCCCCACCCAAATCTCATCTTGAATTCCCACATGTTGTGGGAGGGGACCCAGTGGGAGGTAATTGAATTACGGGGGTGGCTCTTTCCATGCTGTTCTCGTGATAGTGAATAAGCCTCATGAGATCTGATGGTTTTAAAAATGAGAGTTTCTCTGCACAAACTCATTCTTTTTGCCTGCTGCCATCCATTTAAGAAGTGACCTGCTCCTCCTTACCTTCTGCCATGATTGTGAGGTCTCCCCAGCCACGTGGAACTGTAAGTCCATTAAACCTCTTTCTTTTGTAAGTTGCCCAATCTCAGGTATGTCTTTATCAGCAGCATGAAAATGGTCTAATACACTTCGAGACACTCTCCAGGGACTGCAGCTTCTGCTGCTCCTGGGCCTCGGGGACATCCAGAACCACTTTATTAAAGCACCCAAGGCCCAGGGCAGTGACACTGCTGGGCAGGACACCGCATGTTTCCCAGGGACCACCCTCCAGCCACCTCACATGGAGGTCAGGACCAGAGTGCCTGACGCAGGCACTCACATGGAGGCCTCGGGTTTGGGGTGTTTGCTTTAACGTCACTGACTCATGGGACCCCCGCTGTGAAAGCACCTTAGAGACCTTCCAGAACAATCCCAGATCAGAGGGTGACACCCAGGCCTTCCCTGGCCAGGGCAGCACTCGGGCCGGTCCTGACCCCCCCGCTCTTTCCTGACTCAGCCATGGCTGCCTTGTCTGCACTTCATTTTCTTGAAAACTGGGCAGAGTACCCAATGCCCACCTGGCAGCGGGGCCCAGGAGCAGCACCCCCACCTCTCTCGGCCTGTGTCCCTGTCTCCCTCCCCGTCGCTCTCCCTCCTGTCTGTCTGTCTTTGGTTTGAGCTGTCTCCTGGGTCAGGGCGGCCCCGCCTCTCTGATGGGCGGAGGGTCCTGATGTCCTTGGTCTGTCCTCAGCATCTGCTGTGGGACCTCAGGAGAAGCGCCACTCTGGACCCCAGGAGTGGGGCCATCCCCCATCCCAAATAGTGTCCCTCGTACTGGCACAAGGTCCAGGCCCCGGGTGGCCGCCTCTCCAGAGCCTGTGGGACCCTGTGGCCTGCACCACTGGGGCTTCTCACACCAGCCCCTGCCTCCCCGGCACTGGTTCTCTGGGTCTGCCTCTCCATCCACTCAGCCTCACGCCAGCCCCCGCCTCGCCACGCTGGTCCTCCCGGCCTCGCCTCTCCTTTGTGCAGCACCCCTGCCACCTGGCTTTGGTAGATGCACCTTCACCTGCTTCCCTGGACGAGGTGGGCTGCAGGCCACATCCTGTGAAGCGGGTAGGCAGCCCCATCCCAGGGCGTAAGCATGGTGTGGGTGCTGAAATGTTCTCATCTGCGGTTCCCAGGGCCAGCTAGGGGCCAGGCCTGTGCCATCCTCAACATATCACGTTGGGGTTGGGGGGGGGTCTGTGCTCACGGTGGGCTGCGTCACCGGCAGCAGGACAGGGCACGTGCTCCGTACCTCAGGGCTGAGTGCTTCCAGGGCCACCTCCTTGTTCCTCCCTCCTCTCCGCTCCTCCACCGCCCTCTCCCCTCCCACCTTCCGTGCACACTCACTGAGCACTGACAGGGCAGCCTGGGCTCCATGCTTAGACCCCGCACCACAGGTGTCATCCGGAAGGAGCTGGAGAGGCCGCAGTGTGGTCGGAGCTGACTAGGCCCGGCTGCTTGAGAAAACCGGCCGGATCCCGAGTTCAGCTGGGGCCCACACACCCACCGGAAACACACCCAGCAGAGCAGAAACCAGAAACGTGAGATTGTCTACCAGAAACACTTTCACGGCCGGGCTCCATCACGGCTGCACACCCACCTGCTGTCCCAGCCAATGGGGAATGCACGACCCATGCTGCTGCCCAGGCAGGAGAGCAGCAGCTCCCGGCACACACGGCGACTCCCACAGACACAGAAGGGCACACGCCATGGGAGCCACGGTCCTAAAGCTGGGATGAGGTCGAGGAATCCGCAGGTCCCAGGGAAGGAGGAGCTGCCGAGTCTGTGCTTCTCGCCCGGGGCTGCTGTGCAGGCAGACGCACGCTATGTCATGGGCCAGGCCGGACACTTCAGTCTTGGTGCTTTCTGCACGTGTACTGTATTCTGCCTTAAAGGTGTATTTAAAATGCCTGTAGAGGAACAAAATTCTCACTCTGCTGCTGACTGTGTGACCTTGGCTGAACCATATGACGGCTCCCAGCCTGCACTTCCTTACCTGTGTGATGGGAATGATAGCAGTGCCTTCTTCACAACCTCCAGGGAGGTTCCCCAGGAAAACGCCATGGCAGTTCTCAGCCGGGGCCTGGCCGCATGGCTACCGTCGAAGCTCTGCTGCTGGACCTGAAACGCCACGGCCCCAGTGCAAGACACCATCAGTGTGTGCTCTGTGGGGAAGCTGATCCGATGCACCTGGCCTGACATGGATCTTTGTGGGGTCCAGGGCCCGGGTTCTTCTCCAACGCACTGATCTCCTCCATCCCTGGCTCCCAAAATGCACCAGACAAGGAAAACCAGAAGAAATCAGATACAACCCTCAAGCGTTCCAGCCGGGGGGCTGGGATGTGCACACACAGCTGAGTGCAATGGGAGAGGGTGCGGTGTGAGCAACAGAGGCGCCCAGTCTAGGGAGGGCTGCTTCCCACACAGTGAGCACCACACAGGAACCAGAGAGGATTCCAGGTGTCCAGAGAAAACAGCTGGGGCAGGCGGGTGGGGGAGACGCAGTTTGGCCACAGCAGAGGAGGCCGAGGAGGAAGCGGAGGAGGCCGAGGAGGGAGCAGAGTCAAACCGAATCAGCAAGAAGGGTCAGGGCCCTAAATGTTCTCCACGGGGTCCCGACGTTCACCCGCAGCCGGAGTCCTTCAAAGAAAACCCAGAGACCACCTGCCTCCATATTTCCTGCAGTTTTTATAAAAGTGCAAGTTCCTGTATCCGACCCATGATGTGCTGACCGGGAGCTCTGGCAGTGGTATCCGGGGTCTGTGTGTCGACCCTCACTGTCAACAACAGGGAGCCACAGAAGGTTCATGAGCTGGGGAGTAACACGGCCGCTGCTGTCCGTGACTGGGCAGGTGGTGAAGGGGCTCCAGGGAGGGAGCCCAGCCAGTGTGTTTGCTGCTTCTTCATCTTCTGAGAACACGGAGAAGCCCCGTTGGAAGGAAAGGCCTGGGTTAGTATTGATCCAGATGTGGACACAGCTAGCCGATAAGGGAGGGTGTGTGAGACGTGATTTAATTCCTCCCACCAACCGCACATCGCTGCCTAGCGGAAGCCCCCTCCAGGGGTCTCACCTCATACCACAGCCAAGCAGGGGCTGGGGGCTGCCTCCCGCTGGCCCTCTGAGGGCCTGAGTCAGAAGGGTGAGGATGAAACACAGGTGGGAGCTCCCCAGATTCCCCAGAGGGGCTCCCTTCTCAGAGGCGAGGGCTAGCACCTCTGCCAGCCACTTCTGCCCCTGAAGGCCCCAAATCCTGGGAGCGCTTCGGTCCCCAAGAGACTGGGAAGTTGGTCACACTGACAGGGAATTGGTCCTCATTGAAAACATTAGTCTTTCAGCTGTTCCAGGGGAAAGGGGACGGGGGTCAAGGGAAAAGTTCTTAACAACATTTGTGCTGAAAACATGGGGTTGGGGGCAGCAACCCCAAGGTGAGAACAAGCTGAAACCTTTCCTGGGATGCAGACGCCTTCACAAGGCCTCACCCACCAGAGCAGAGATGGCCTCAGCCCTCAGGCCATCCGGTGAGGGACGGACAAGCACCACGGGCGCCCACAGGCGTGGCATCATCCAGGCACCCAAAGGAACGTAGTCTGATGCACTCTGGGCACAGGGTGCCTGGGTACAGGCAGAGTGGAAGCAGCCAGTCACAAAAGGCCACATCCAGCCTGATGCCATCCACATGAAATGCCAGGCATAGGCAAAGCCTCAGAGGCAGAGGGAGGTCAGCGTTGGACTTGGCCTTCTGACTTTCGGTTAGAGCGTTTCTCATTTAGGGACATGCAATGATGCTGTCATCACCCCTAGGCAATGGGCACTTATGCTGTGGCTGTTTCCTGTGAATGCACTTGCACACGGGACCTGTGGCATCCTGTGGGCGTCCTGTGAGTGTTGTGTGGGTGTCCTGCATGTGTGTGCACATGCGAAGGCCCTTCCTAGCATTTCTGCTGTGTGTACTGTCGGATACGGTCCTGGAAGTGGACTCCACGTTGCCGTGATGATGTGTGGGGCATTGGTGCCATAGCCACGCCTTCTGAAAAGTCATGCCCATTCAGGCTCCTACCCTGAGAGCGGAGTGGGTTTGCTTCTCCACACCGTCCTTAGCACGCATATTCCCAGTGGTTCTCATGCGTGAGCAACAGTCACAAAACAATGACGTGTTGTGGTTTTCCTGGCATGTCTTTGGTTCTCACTGGCCCAGACTGTGGCCTCCGCTTCATGGACAGAGGGACTAAGAAAGAAGCTTGTGTCTGGCTTGCCACGTGTAGAGGCAGAGGCATGGCCCACACCCCTGCCTCAGTCAGCACAGGAGGTGAGAGACTTCTGCCCCCAGGGAAAGGAGAAGTTTTCTCTCCTGGCCCTCCCATGATCTCTCCTGCTGAGGCTGCACACTGAGTGACAGGCCAGCCACTGCCGCATGCTACCTGTTTGCCACTCTGTGACCTTGGGCTTGCCCCTTCAGTCCTATGAGCCTCATCCACAAAAATGGAGACACATTCCCTGTGCAGCAAATGGTTTGTGCAGACTGAGAACATGTCTGCAAAAGCACCTGGCATGCAGCAAGTGCTCACTAAACACTGAGCAGCTGCATCATCATTGTCATAGTCATCACCATCGCCACCACCATCACCATCACCACCATCGTCACCATCACCATCGCCATCACTATTACCACCATCATCACCATCATCACCATCACAACCATCACGACCACCACCACCATCACCACTATCACCATTGTCACCATCGCCACCACCATCACCATCGTCACCATCACCATCACCATCACTATTACCATCATCACCATCATTACCATCACCACCGTCGTCACCATCACCACCACCATCACAACCGTCACCACCACCACCATCACCACCATCACCATCGTCACCATCACCATCACCTTCATAGTCATCATCATCACCATCACCACCATCACCATCATTATCATCATTGTTACCATGACCATCACCACCATCATCCTCCTCACCACCATCATCACCATCATCATCATCATATCACCATCACCATCACTACCATCGTCATCACCATCACCACCACCAACACCACCATCATAACCATCATAATCACCACCATCATCACTACCACCATCATCACCATCATCATCACTATTGTTATCACCACCACCATCATCCTCATCACTACCATCACTATCATCACCATCACCACCATCGTCATCACCATCACCACCACCACCACCACCACCATCACCACTATCATCACCACCATCATCATCATCACTATTGTTACCACCGCCATCATCATCACCAC → G