Variant · Deletion

FANCA NC_000016.10:g.89807755_89816658del

CI-VAR-00169281Explore in graph →ClinVar 974077

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
974077	Pathogenic	no assertion criteria provided	0	Fanconi anemia complementation group A	germline	1	Feb 28, 2020	clinvar

Nomenclature

Record

Gene: FANCA
Type: Deletion
HGVS g.: NC_000016.10:g.89807755_89816658del
Assembly: GRCh38
Position: chr16:89807752-89816656
Ref / Alt: GGACGCCTGTAGTCCCAGCTACTCGGGAAGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGTGGAGCCTGCAGTGAGCCGACATCACGTCACTGCACTCCAGCCTGGGTGACAGAACGAGACTCTGTCCCTAAAAAAAATAAATACATAACAAAAATTAGCTGCGTGTGGTGGCGGGCGCCTGTAATCCCAGCGACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCTGGAGGTGGAGGTTGTAGTGAGCTGAAATCGTGCCACTGCACTCCCACCTGGGCCACAGAGCGAGACTCCGTCTCAAAAAAAAAACAGACAAAAAGCAAACAAAACCAAAACACCATAAACGTTCTCTTGAAATAATAAAGCAATAGTTCCTCCAGGTCTAGTCTAGTATAAATATGCAATGCAATCTAGTCTAGTACAAATTATATGTCAAAGCCAGAAATCAAACCCGTCTGATTCTGGGCTTTGAAATATAATTTATACTAGACTAGACTGCAAAAACAGTAACACTGAATCATCATTAGCACGCTACCTTTCCAGCAGCTCTTGCAGGCTCACAATGCCTTGTACGTGAAGATGCCACACCGCTTCAAGCAACAAAGAACTCTGAAAAACAAAACAAAACAAACAAAAACAAAAACAAAAAAACCCCCAGCATTCTGAGTCCTTTATGAATGCATTTTCCTACAAAATGTTCAACTTAGGTTCTTAACCATGCCGTATTGAAAATTAACCTCAAGCAAAAACTTAGAGCCTGAAACACATCTTTTTTTACAAAGCTGTACTGGTTTTCAAACTCCCTGGCCTTTGGGCACCCACACACCGTTGCCCAACACTTGCTTCTCTTCCTTCTCTCTTCCTACGCACTGTAGCCTACTTCTAACCCTTTCTCCACACTACAGCCAACACAGTATTACACACACTGACATGACAGTCTCTCCTTCAGAAGCCTTCACTGGCTCCTCGAAGCTGCCAGGACAAAGGTCAGGCTTCAGTGTGCCCTGTGCATGTCCCTTGTCTTTCTCACTCAACCCTCTCCCATTTGATAAAACAGGATCTGCTTTAGCCACTCACTGTGAACACTGTGCCTGTCACACTGCCCTGATCTCCCTGCAGCCTCCCCTTCTCATCCCCCTAACTCACACTCTATTTTTTTTTTTTTGAGACAGAGTCGCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCCATCTCGGGTCACTGTAAGCTCTGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGTGCCTGCCACCACACCCGGCTAATTTTTTCTATTTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGGCTCGATCTCCTGACCTCATGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGGGCCCGGCCCCTAACTCGCACTCTTCACAGTCCGTGCAGGAAGGCTTTCCTAACTCTCCAATCTGATATGCATGTCCAACATCTTCTTCGCAAATCTGTGAGCACATGAATCATCGCACTTCTTGTGGATTTAGTGGCTTGTTTCCCAAGCTACGTGATAATGAGGGCAGGGACCAAAGCAATAACTGAAAAATCTAATGAATTCTATAATGTATGCTGGATAAAAGAATGGGAAAGGCCGGACGCAGTGGCTCACACCTGTAATCCCAGCACTTGGGAGGCCAAGATGGGCAGATCACCTGAGGTCAGGAATTGAAGACCAGCCTGGCCAACATGGTGAAACCTCATCTCTACTAAAGATACAAAAATTGGGCAGGGCGCGGTGACTCACACCTGTAATCCCGGCACTTTGGGAGGCCGAGGTGGGCAGATCATCTGAGGTCAGGAGTTTGAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAAAAAATTAGCCAGGCATGGTGGCGCATGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCGGGAGAATGGCGTGAACCCGGGAGGCGGACGTTGCGATAAGCCAAGATAGCACCATTGCACTCCAGCCTGGGCAACAAGAGCAAAACTCCATCTCAAAAAAAAAAAAAGATACAAAAATTAACTGGGCATGGTGGCACGCGCCTGTAATCCCAGCTACTAAGGTGGCTGAGGCAGGACAATCGCTTGAACCTGGGAGGCAGACGTTGCAGTGAGCCAAGATTGCGCCACTGCACTCCAGCCTGGGCGGCAGAGCAATATTCTGTCTCAAAAATAAAAATAAATGCCAGGCGCGGTGGCTCACACTTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTCTGCTAAAAAATACAAAAAATTAGCTGGGCGTGGTGGCAGTCACCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGTGGGGCTTGCAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGTGCGACAGAGCGAGACTTCGTCTCAAAAAAAAAAAAAAAAGACCAGCCTGGGCAACAAGGCGAGACCCTGTCTCTGGAAAAAAAAATTACATACATTTTTTTTTAATAGTTTACTATACTACCCTGGAAAATTCTCCATACTAATATACCCAAGGCTAAACGTGTTTTTCAATATATTCTAGTCTAATAAATATTACTAATGATAGGTGAATAGGGACAAAAAATGGCAATTGAAGGTACTTCTTTCCAATCCACAGATGATTTCTAAACCCTTTTTCATCCACTCTCTGTAATTAATGAGAAGCTTGGAGAATTCCCAAGAAAACCCAGGTACTCTGTTGCCTCCATCCAGATCAACAGAACATTGCCTGGAACACTGGAGAGTCAGATTTGCAATCTCAAATTTACCTGTATTTTCCATAATTCTTGACAGAAGGAAAGACGGGAGAACATACTGTGTGCCAATAAATACTGAGCAAACTCTAACAGGGAAGACAGCTTCTTCTGAAAAGAGAGATTACATTTTTTAAAAAACAAATTACCTGAAACAATACTAAAGCTATGTCCTATTTTCCCAACCAGCTTAAAAGTAACAACGGGCAGGTTTCCTCATCTTTGCTGGTGTCTTACTCTCTGCTCCACAGTCAGCAGCACAGGGTGACTGGTCTCCGCTGGAGCCGTGCAGATCTGTCCCACGCTAGAGGCAACCATCCCGGCTGAGAGAATACCCACGGGAACCCCCAGCCTTGAGGCTTGATCCTGCAAAGCAGAGCCTTAAACACAAAACAAAACCATAGCTTTCTCTTAACACATGAGACAAAATCTAAAACCAAAGACTTGCTGTTTAAAATGCCTTATTTTAAGATGCAGCACAAAAAAAATTGCCTTTTAAACGGGGAGAATAGATGCAAAGGGAAAAACATGAGATAAAAATGAGAATTTGATGATCCAAGCAGCTCACAATAAAACTGGTGGCAACACCTGAACCCAGAGTTATACATTGGTATTTGTTACGTTTCCCATGACACAAAAGGAGCAAGATAAAGAAATATATTCTGACCAAGAACTTTATCATCTTTTTACAAAGGAGCACAATAAATTGAGAACTGCAGCAGGCTCTTTCAATTACATTGTTTTTCTAATTACTTCAGAGATAAGCCTGCCCCTGTTGACTCACATTGATGGTTGTGATAAAATTAGGCAGGGATTTCCCAACATTCTGCCATGCACCTGGTGGGCAGGTGCAGTCACAGCTGTGCTCAGTCCGCAGGCCACCAAGTGGAACCTCACTAACAGCCTGCAGGCAGCCACCATTCTCCTGAGCAACCAGCCACTGGTCTGCATTCAATAAAGTGAGAAACGGTGGGCAACCTGGAAGCAGGCAATGCCAAGAAATCATTTTCTAATTTATTTGTCTTCCAAAATTAATTTTTTTTTGTTTTATTTTTTTGCAATGGTGTCTTACACTGCCGCCTGGACTGAAGTGCAACGGCGCCATCTCAGCTCACTGCAACCTCCGCCTCTCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACGCGTCACTACGCCCAGTTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTCACTATGTTGGCTAGGCTCGTCTCCAATTCCCAACCTCATTAATCCGCCCGCCTCGGCCTCCCATACTGCTGGGATTACAGGTGTGAGCCACCACGTGAGCCAAAATTAATTGTTTAAAGAAACCGGGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATTACAAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCTGTCTCTACTAAAGACACAAAAACAAAATTAGCCAGGTTTGGTGACGGGAGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCGAAGAATGGCGTGAACCCAGGAGGCGGAGTTTGCAGTGAGCCGAGATCACGCCACTACACTGCAGTCTGGGCGACAGAGCCAGACTTCATCTCAAAAAAACAAAACAAAAAAAAACTGGAGGCCAGGCTCAGTGGGTCCCTCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACCTGAGGTCGGGAGTTTGAGACCAGCCTGACCAACATGGTGAAACCCTATCTCTACTAAAAATACAAAATTAGCCAGGCGTGGTGGTGCATGCCTGTAATACCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTTAACTAGGGAGGCAGAGGTTGCGGTGAGTCGAGATCACACCATTGCACTCCAGCCTGGGTAACAAGAGCAATACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAACTGTTAACTGCAGTACGAACCTGTTATTGTAATGTACTGGCTCTAAAAACACATTATCAATACATAAGTAAAAACATTTACAGGCTGGTTGCGGTGGCTCATGCCTGTAATCCCAACACTGCAGGAGGCCGAGGCGGGTCGATCACGAGGTCAGGAGTTTGAGACCAGCCTGGCCAAGATGGTGAAACCCCGCCTCTACTAAAAATACAAAAATTAGCTGGGTGCGGCGGCGGGCACCTATAATCCCAGCTATTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCAGAGTTTGTAGTGAGCCGAGATGGCGCCATTGCACTCCAGCCTGGGCGACAGAGCAACACTTCGTCTCAAAAAAAAAAAAAAAAAATTTTACAATAGTTCTAGAAGCTTAAAATTATAGTACGAGAAATCATCAGCTGCTGGTGAAATTCTCGGTAGAAAAGTAGACAGATGGGGCACAGTGGCTCATGCCTGCAATCCCAACACCTTGGGTGGCTGAGGTAAACTGATTGCTTGAGCTCAGGAGTTTGAGACCAGCCTGGGCAATATGGCAAAACCCTGTCTCTATGAAAAAATTAGCCAGGCATGGTGGCGCACACCTGTAGTCCCAGCTACTCAAGATGCTGGGGTGGGAGGATCACTTGAGGCCAGGAGGTCAAGACTGCAGTGAGCCGTGATTGCACCACGGCTCTCCAGTCCAGGCAACAGAGTGAGACCCTGTCTGTTAAAAAAAAAAAAAAAAGTAGACAATGCCATTTTCTGTTCTGAGACAGAGTTTTGCTCTTATTGCCCAGGCTGGAGTGCAATGGAGGGGTCTCGGCTCAATGCAACCTCTGCCTCCCACGTTCAAGCAATTCTCCTGCCTCAGCCTCCTGAATAGCTGGGACTACAGGCACCCACCACCACACCCGGCTAATTTTTGTGTTTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTCGTCTCGAATCCTGACCTCAGGTGATCCGCACACCTCAGCCTCCCAAAGTGCTGCGATTATAGGCGTGAGCCACTGTGCCAGGCCAACAATGCCAATTTCTAGTCATTTGTTTCCAATGTGTCTCCATAGGAAAGTTTTTTTATCTACAAGTCTTTTACTGTGTGTGTGTGTGTGTGTGTGTGTGTCCGTGTGCACGTGCGTGCATGTACTAACTATATCTTTAGCAGAAAAAAACAAACTCAAAAATTAATGAATTAAAGGTTTATCTGTGTGGCTGAGCTTGGTTCCTTGGAATGATAATATGCAATTTGTGAAATTCAAATACAATCATGGCAGTGAAAATCTGTATCATTTGCCAATGACATTCAGTGACCAGTTGTCAAGGGAGCGCTATTACTGAAGGTTATTTTAACAGAAACAAGTCATCACATAAGGACGTGAAGGATCAGAAAATAACTTACTGTTGTTGACCCAGAACTTACCCTATCTCCCACTCTCAAACTGGGGGGAGAAGGAGGTACCTAGAAAATTGTTCTCCCGTCTGCTCTCCTGGGCACACCACAGCCTGTCTCACTACTTCCATGAGCAAGGGGCACATCCCTGCTGTTGCTATGTCCCATGTTTTTCCAAGGGACACTCTGGGTCCTACTGCTTCTGAGTCGCAGGTTGAATCAGACGCTGTTTTTAAACACAGCATCGTAAGAAGCCCAAGAGCAAGTCACACAAACATCCCATAGAATTTGCGACTACACACACCAGTGGAAACCCATCGCCTGAGAAAATTTACATTTCTACTTAATTTAGCAAACTATGGTTACTATATAAAAACCCTTCTGCAATTCAAAATAGAGAAAATGAAGCTATAACTTACCTATAAATGAACTAGAATGATTAGCATAGGCCTCAGAACTGTCACAGTCAATCACTTTGCTGAGAGACAATTTTTTACACAGTGGACCTTCTACCTAGAATCCAAAACACAACAAACTCCATTTAAAAAATTCAAGCTCCAGGCCAGGCGTAGTGGCTCACGCCTGTAATCCCAGTACTTTGGGAGGCCGAGATGGGCAGATCACGAGGTCAAGAGTTCGAGACCAGCCTGGCCAACATAGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGGAGGGCATGGTGGCGCGTGCCTGTAGTCCCAGCCACTCGGGAGGCTGAGACGGGAGAATCACTTAAACCCGGGAGGTGGAGGCTGCAGTGAGCCGAGATCACCCCACTGCATACCAGCCCAGGCTACAGTGTGAGACTTTGTCTCAAAAAAAATAAATGAAAATAAAAAATAAAAATAAAAAAAATTCAAGATCTGTGCATAAACACAACCTGTGTGTAAGTAATGCTTCCCTACTGGGCTATTTTCCTTTTTTTCTTTTTTGAGAGGGAGTCTCACTGTCGTCCAGGCTGGAGTGCAATGGCGGGATCTCACTCACGGCGACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGCAGCTGGGATTACAGACACCTGCTACCATACCCGGCTAATTTTTGTATTTTAAGTAGTGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACTCCTAACCTCAAGTGATCTACCCACTTCGGCCTCCCAAAGGGCTAGGATTACAGGCGTGAGCCACCACGCCCGGCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGTGAGACAGTCTCACTCTGTAATCCAGACTGGATTGCAAGGGGCGTGATCTCGGCTCACTGCAATTTCTGCCTCCCGGGTCCAGGTTCAAGCAATTCTCCTGCCTCAGGCTCCCGAGTAGCTGGGATTAAAGGCGTGCGCCACCACACCCAGCTAATTTTTGTATTTTCAGTAGAGACCGGGTTTCACTATGTTGGCCAGGCTGGTCTCGAACTCCTGACCCTGAGTGATCCACCCGCCTTGGCCTCCCCAAAAGCTGGGATTACAGCCCTGAGCCACGGCGCCCGGCCTGTTTTTTTGTTGTTGTTGTTTTGTTTTTAATAAAAGAGGCGGGGTCTCACCCCGTTGCCCAGGTTGGTCCAGAACTCCCGGGCTCAGGCGACCCTCCCCTCTGCGGGCCAGGCCACCGCGCCCGCCGCCTCGGGTGTTTTCTTAGGAAAGCTGTGCGGTGGCTGGACTCAAAAACCCCGAACCTAAATCTGCCCGCAGACGGACACCAGCTTCCTCTTACCTCAAGCAAAAGGGCATTCAGGTCCTGATGGCTTCGCAGGAGGCGCACAGCTGATTCCTTTAATTTCTGTGCCCTTTCAGGATTATATTTTTCCCTCTTGACCCTTCCCGCTACGGAGAGAAGTCGGTTCGAAACCATCACAGCACAATTCACACACGGGGTCCCCGGCCCGACGCGCAGGTGGACGCCGCGGAGAAACCCACCAGCGACACCCTCCCGAAGAGGGGCCGGGGCTCCTCCCCAGGGCGCAGGTCTCGGGAAACTAACGGAGACGGCCCCACCGCGGACGCCGGGGAAGACGGCCCAGGAGGGCCCGAGGCAGGGGAGCCCGGGGACGGCTGGCGAGGGGCGGCCTCTGCGCTGAGGGGAGCCCCAGGCCGCGCACCCCAGGCCCGCCTGACAGGGCGGCCGGCGGGGGCGGCGTTCGGGAAAGAAGGGAGCGCCCCGCGGGCGGCGGCTGGGGGCGTCCGCCCAGGCGCAGGAGGGGCCGGGTCCGAGGCAGCCGCGCCGCCCCAGCCGGGCGCCCACCCCGCACAGCCCCCCGGGCGCGGCGTCCGGGGATCCGACCGGCGGAGGCTCTGGCGGGAAGGGATCGGGGAACCGGCGAAACCGTCCCGGGCCGGACGCCGCCCACTCCCGCGGCCTGCCGCGCCCACCTACCCAGCAGCTCGGCCCAGGCCCTCCGGCGGCCCCCTGGGTCCTGGCCCGAGGCGGAGTTCGGGACCCACGAGTCGGACATGGCCTTGGCGCCTACAGCCCCGGCGGCGGCTCCCTGCGCCC → G