RET NM_020975.6(RET):c.375C>A (p.Val125=)

CI-VAR-00018255Explore in graph →p.Val125=NM_020975.6:c.375C>AClinVar 95997 rs1800859

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
95997	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Hereditary cancer-predisposing syndrome; Pheochromocytoma; Hirschsprung disease, susceptibility to, 1; Renal hypodysplasia/aplasia 1; Multiple endocrine neoplasia; Aganglionic megacolon; Multiple endocrine neoplasia, type 2; Multiple endocrine neoplasia type 2B; Sarcoma; Thyroid cancer, nonmedullary, 1; Hepatocellular carcinoma; Familial cancer of breast; Uterine corpus endometrial carcinoma; Familial medullary thyroid carcinoma; Multiple endocrine neoplasia type 2A; Clear cell carcinoma of kidney	germline	22	Jun 01, 2026	clinvar