VPS13B NM_152564.5(VPS13B):c.3866C>G (p.Thr1289Ser)

CI-VAR-00018247Explore in graph →p.Thr1289SerNM_152564.5:c.3866C>GClinVar 95851 rs145569846

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
95851	Conflicting classifications of pathogenicity	criteria provided, conflicting classifications	1	Cohen syndrome; Inborn genetic diseases; Lung cancer; Familial cancer of breast	germline	12	Jan 27, 2026	clinvar