OPA1 NM_130837.3(OPA1):c.629C>T (p.Ala210Val)

CI-VAR-00018242Explore in graph →p.Ala210ValNM_130837.3:c.629C>TClinVar 95729 rs34307082

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
95729	Benign	criteria provided, multiple submitters, no conflicts	2	Autosomal dominant optic atrophy classic form; Colorectal cancer; Sarcoma; Melanoma; Malignant tumor of esophagus; Lung cancer; Cervical cancer; Ovarian serous cystadenocarcinoma; Cholangiocarcinoma	germline	13	Feb 02, 2026	clinvar