RPGRIP1L NM_015272.5(RPGRIP1L):c.3548C>G (p.Ala1183Gly)

CI-VAR-00018240Explore in graph →p.Ala1183GlyNM_015272.5:c.3548C>GClinVar 95693 rs139974543

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
95693	Benign/Likely benign	criteria provided, multiple submitters, no conflicts	2	Joubert syndrome; Meckel-Gruber syndrome; Meckel syndrome, type 5; Joubert syndrome 7; Nephronophthisis 8; Lung cancer; Thyroid cancer, nonmedullary, 1; Malignant tumor of esophagus; Clear cell carcinoma of kidney; Gastric cancer; Ovarian serous cystadenocarcinoma; Thymoma; Melanoma; Adrenocortical carcinoma, hereditary	germline	15	Jun 01, 2026	clinvar