Variant · Snv
NPHP4 NM_015102.5(NPHP4):c.3876C>T (p.Gly1292=)
CI-VAR-00018239Explore in graph →p.Gly1292=NM_015102.5:c.3876C>TClinVar 95685 rs115526767
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 95685 | Benign/Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Nephronophthisis; Senior-Loken syndrome 4; Nephronophthisis 4; Kidney disorder; Colon adenocarcinoma; Colorectal cancer; Sarcoma; Gastric cancer; Uterine carcinosarcoma; Malignant tumor of esophagus; Lung cancer; Thymoma; Nonpapillary renal cell carcinoma | germline | 8 | Feb 01, 2026 | clinvar |