Variant · Deletion

BRIP1 NM_032043.3(BRIP1):c.918+2790_1121del

CI-VAR-00164806Explore in graph →NM_032043.3:c.918+2790_1121delClinVar 944523

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
944523	Likely pathogenic	criteria provided, single submitter	1	Familial cancer of breast; Fanconi anemia complementation group J	germline	1	Sep 05, 2019	clinvar

Nomenclature

Record

Gene: BRIP1
Type: Deletion
HGVS c.: NM_032043.3:c.918+2790_1121del
Assembly: GRCh38
Position: chr17:61801271-61805677
Ref / Alt: ATCTAGAAGATAGTTGTAGGGACAAAATATGATGTCAGCATCTTGTATTAGTTCTCGGGCTGTGTAATATGGACAGGCCTTTAGTTTCTTCCCCAGGCTGACAAGTTCTTCTATATCCCAGGCTTTGCACATCCCTTGGAAAGTCTGTAATGTGTGCTGATCACTAATTTTATGAACTCCATGATAAAAATAGCAGGATTTTCCCTAGAAACAAATATGCATAACTGAAATGTGAACCAATATTAGCATAGAAGGAATAAAATAAGCTTATCTCAGAATTTGAGGAACATCATTAAAGCCACAAGGCTAAGATTTTACTGGCTACGCCACCACACCTGGCTAATTTTTTGTCTTTTTTGAGACAATACCATAGCTACAATCACAACGAAGTCTGGTTGACTCAGACTTAGATAGAAGTCCAAATCGGAAGAGCTCCAAATACCCTAAATTAACTTGAAAAAAATTTCTTTTAAATATGTTTGTTATGCCTTTTTTTTTCTGATTAAACTGATGTTAGGCATGAAATACTTCTGAAAGGATTCACAAAACAATGGTATCACTGGTTGCTTCCAAGGATGAGAATTAAGTGACTGGGCACAGGAGTGAGAGATTTTTCTCTGTAGACCCTTTTGTACCTTTTCAACTTTGAGCCATGTGATAGTATTTCTTATTCAAATATAAATAAGAAGGAAGGAAGGTAAGTAGGTAGGTTGGAATGTCCTAAGGGGAAAAAAAGAAAGTAAGAGTATTCACTACAAAATATTCAGGAGTACCAAAAAAAGCCTAAATTATCCATAATTCTATTACACAAAGAATGCACTAGAAACATTTTGGTGTATTTCATTTCATATTTCTTCTATACATGTGTATATAAGGATATCTCTACAATGTGACCCAATATTAAAATAACAAGAACAAGCAAGGCACGATGACAGGTGTGAGCACTTTGGGAGGCTTAGGCAAAAGGACTGTTTTAGGTGAGGAGTTTGATACCAGCCTGGGCAATGTAGCAAAACCCTGTCTCTACAAAAAATAAAAAATTTTCTAGGATTGGTGGCGTACATCAATGGTCCTAGCTACTCAGGAAGCTGAGGCAGGAGGATCACTTCAGCCCAGGAGTTCGAGGATGCAGTGAGCCATGATCAAGCCACTGCACTCCGGCCTGGATGACAAAACAAAGCCCTATCTCTAAATAGTAATAAAAACAAGAACAAAGCAAATGTTCCCCAGGCATTGAGGATTATTAACAATTCAGCCACAATAAACAAAAATTTTTATAAAGCATATTCCCTTTGTTTTCTTCTGTCTAGCGTATTAAAAATCATACAAGGAAAATCTTGACATCACTAAGCATCTTTTCGTTGCTGCTCATATATGTACATTGAATTAATGTGCCATAGCTGATGAACCAGTTTTCTTATTACTGGGCTTATAGACTGTTACCAATTTCTGCTTTAGACATAAGGCTGCAGTGAGCATTCTTATGCTGGTTTCTAAATATTTTCTTAGTCTATATTTTTAGAAATGGCATTATGGGATCAGACGCTACAAGGTATTTTTAAGTTTCTTGAAAACATATAGTGAAATTATCCTCCAGAAAGTATATATTGCTTTGCATTACCCTTTTCCCACATCCTTATCAACACTGGTGTTATCTTTTGTTATCTCTATCTTAAAAGTAAAAAATAGAATCTTGTTTTGATTTGTATTTTTTATAGTTTCTAGCAAAGTTTAACATAGTGTTGTATGAATAGTCTAACAAGGTTCAATAGTAATTTGTGTTTCTTCTTTTATGTTATCTACTAATGCCCTTTGCCATTCTATTACCTTTTTTTTTTTCAGAGATGGGAGTCTCACTCTGTCACCTGGGGTGCAGTGGCACGATCCAATCTTGGTTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTTGTGCCTCAGCCACCAAGTAGCTGGAACCACAAGTGCATCACCACATATGGCTCCTTTTTTGTAGAGACAGGGTTTTGTCATGTTGCTCAGGCTGGTCTTGAACTCCTGAACTCAAGCGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGGATTACAGGCATGAGCCACTGCACTCCACCCCATTCTATCACTGGAAATAAAAAAATTTCATTACAGGCTGGGCACAGTGGCTCATGCCTATAATCCCAACATTTTGAGAGGCCAAGGCCGGAGGACTGCATGAGCCTAGGAGTTCAAGACCAGCTGGGCAGCACAGGGAGACTCAATCTCTACAAAAAAACAAAAAAAATTAAACCGCAGTGAGCAGTGACCACGCCACTGCACTCCAGCCTGGGCAACAGAGTGAGATCCTGTCTCAAAAAAAAATACTCATTATGTGCATTAATAAAAAAATAAAATGTTTGATAAAACCCAGCCCTAACAAGTGTCTCATATACTATTAAAAATGTACAAAATTAGAAAAGTATATATATTTTTAGTAGAAGTATAAAATTCTAGTAGTAGAAGTACATAGGCAATTTGTCAAAAAACTACCAAAATTTAAAATTTTACCATTAATGTGAATAGATGTACCCTGTACTGTTAAATAGCCAAAAAATTGAAAATTAACCAAATGTCTACCCATAAGGGACATGTTAAATAAATTATGGTAAATTAATACAAAAACTTTAGCCCTTAAAAATGATTTAGATTTGTCTATGTGTTGATTAGGCTCTCTATGTTAAGTGAGAAAAACATGTTGAATAACGTGTATAGAATGATTAAATTCATGTAAATTGCTTTTTTAAAGAATATGTGCACATACATTATAGCAAATACATTTTTTAAACATTCTGGTAGAATAGATATATAAAATCTTACAGTAGTTACCTTAAAGGATTAAGGAGATGGAGGATCTAGAAAAAGCCTCTCTTTTCATTTTCTAACCACATACATGTACTACTTCTCTTTTTCAATTGTCATTGGAACTAAGTGGTAGAATAATGGGCCACTTTTATTTTAATTAATTCTACTATTTATTTTAAAACGATTTTGAAATAAAAATATTTATTTTTCCTAGTTTGCTATCCTTAACAAAAAACAACCATACATAAAATATATAAATTATATCAGGGATAAAAGACTTTGAGGCAGCTATATACATATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGTGTGTGTACATACACATACATATATACATATGGGTTCAAGCACTTCTCATGCCTCAGCCTCCCAAGTAGCTGGGATTACAAGCACGCATCACCATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACAGGTTTTGCCATGTTGGCCAGGCCAGTCTTGAACTCCTGACCTCAAGTGCCCACCTCAGCCTCCCAGAGTGCTGGCATTACAGGCATGAGCATCATGCCCGGCCAATGTATTTTTTACAAATACATAATAATTTCCCCATATATATATATTCAAAATATTTTTGTCTAATAATTATTAAAATTATAAAATATAAAAATAATTAGTCTAACAAGGTTCAGCAATAATTTGAATTTCTTCTTTTAGGTTATCTACTAATGTCCTTTGCCATTGTATTACTGGAAATAAAAGATTTCATTACAGGCTGAGCGCACTGGCTCATGCTTATAATCCTAACACTTTGAGAAGCCAAGGCAGGATGAAATGTCTCTCTCTTTCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTAAAATTAAATTGTATTTGTATACGTCTGTATAATAAATTAAATTGTATATATATACACACACATATATATGCATATATATAATCTTTACATGTATTTTTATCTATGAATTATCCAAAAGGAGAATCCGTGTTTTCAAAACATACATACATCAATACATACACAAATGTATCTAGATATTGCTAGAAACAAAGTAAACCATAAGAGATTCATAACCTATAAAAGAATGTCAGCAAATCAAAGGACAAGACATGAATAGCTGAGGACCAGTTCTCCTAAAGCTTTGTATTCAGCCATGTTAAAGGATGATACCTGTTAGTCCTCCAAAGTATTAAAAATAAAAATTAGGAGGAAAGGACTCATCTAACTATATTTATTTAGGCCATTTTCTACATTATTTTCACTCACTTTCTCTAACCTCTACTGTTCTTATTCTTCATACTGTGTCAACTTCTCCCTACCTCAATGCCATCTTTGGATTTTGTTTCTAGTGTAACCAAAATAGCAATGGATGAGGAATCAGAAAATTTGGGTTCTGGTCCCTCCTTGCTAATTACTTGTCTGACTGAGAAAACTCCAGGGCCCATTTTTCTCATGTGACTAAGCATCAAAAGAATATTTGAACCAGAAGGCTTGTAAGATTCCTTCTGACTCACTGACTATATCATCTCTAAAATT → A