DHCR7 NM_001360.3(DHCR7):c.964-1G>C

CI-VAR-00018153Explore in graph →NM_001360.3:c.964-1G>CClinVar 93725 rs138659167

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
93725	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Smith-Lemli-Opitz syndrome; Inborn genetic diseases; DHCR7-related disorder; Acute myeloid leukemia; Malignant tumor of urinary bladder; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Uveal melanoma; Sarcoma; Ovarian serous cystadenocarcinoma; Thyroid cancer, nonmedullary, 1; Cholangiocarcinoma; Cervical cancer; Cystic renal disease; Thymoma; Melanoma; Familial cancer of breast	germline	68	Jun 16, 2026	clinvar