Variant · Snv
CDK16 NM_006201.5(CDK16):c.727C>T (p.Leu243=)
CI-VAR-00018149Explore in graph →p.Leu243=NM_006201.5:c.727C>TClinVar 93666 rs145117961
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 93666 | Uncertain significance | criteria provided, single submitter | 1 | Thyroid cancer, nonmedullary, 1; Melanoma; Acute myeloid leukemia; Malignant tumor of esophagus; Nonpapillary renal cell carcinoma; Familial pancreatic carcinoma; Lung cancer; Uterine corpus endometrial carcinoma; Gastric cancer; Cervical cancer | germline | 4 | May 20, 2013 | clinvar |