GBA1 NM_000157.4(GBA1):c.115+1G>A

CI-VAR-00018127Explore in graph →NM_000157.4:c.115+1G>AClinVar 93445 rs104886460

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
93445	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Gaucher disease; Gaucher disease type II; Gaucher disease type I; Gaucher disease type III; Gaucher disease-ophthalmoplegia-cardiovascular calcification syndrome; Parkinson disease, late-onset; Young-onset Parkinson disease; Melanoma; Clear cell carcinoma of kidney; Sarcoma; GBA-related disorder; GBA1-related disorder	germline	23	Feb 01, 2026	clinvar