CDH1 NM_004360.5(CDH1):c.812_833-564del

CI-VAR-00164564Explore in graph →NM_004360.5:c.812_833-564delClinVar 933763 rs1960785868

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
933763	Likely pathogenic	criteria provided, single submitter	1	Hereditary diffuse gastric adenocarcinoma	germline	1	Sep 23, 2019	clinvar

Nomenclature

Record

Gene: CDH1
Type: Deletion
HGVS c.: NM_004360.5:c.812_833-564del
Assembly: GRCh38
Position: chr16:68810317-68811117
Ref / Alt: TCTGTCATGGAAGGTGCTCTTCCAGGTATATCCACTAATGAGAATCTGAATACTCAGAAAGACTCTTAGGTTCTTTGGACCCCAAAGTGTTGTCCAAGCCCAAAGGTTGTGTAACTAAAGCTGATCCTTCCTACGGACAGAACTTCTTGGCAAGCCATTGTTGTGTTATATGCATGTGTGTAACAGTCTACCTGTGGAAACATATAAAATAGGGAGAGTTTAAGAACAATCTTCCCTTTTTTATTATTAATTTTTTTTTTTTTTAGGCTGGGCATGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGATGGGTCACCTGTGCTCAGGAGTTCAAGACCAGCCTGACCAACATGGTGAAACCTCGTCTCTATTAAAAATACAAAAAAATTAGCCGGTCGTGGTGGCGGGGGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGGAGGCGGGGGTTGCAGTAAGCTGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGATCCAGACTCCGTCTCAAAAAAAAAAAAATTTTTTTTTCAGAGACAGGGTCTTGCTTTGTTGTCCAGGCTACTTTCAAACTCCCGGGCCCAAGCAATCCTCCCACCTCAGCCCCACAAGCTGCTAAGATTATAGGCATGAGCTACTATACCTGGCTAAGAACAACCTTCCTAATTAAGGAACAGATCTTTACCAGTACCTTAAAGCCCTAAACAATCCCCCTTGGTCACATTCTTTTCTCTCCTCCATAAAGATAACCACACCCTAGG → T

Per-assembly coordinates

stop
68811117
start
68810318
source
clinvar
assembly