Variant · Snv
PDE6A NM_000440.3(PDE6A):c.1963C>T (p.His655Tyr)
CI-VAR-00018043Explore in graph →p.His655TyrNM_000440.3:c.1963C>TClinVar 93010 rs78775072
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 93010 | Conflicting classifications of pathogenicity | criteria provided, conflicting classifications | 1 | Retinitis pigmentosa 43; Retinitis pigmentosa; Uterine corpus endometrial carcinoma; Sarcoma; Lymphoma; Melanoma; Cervical cancer; Malignant tumor of esophagus; Ovarian cancer | germline | 6 | Feb 01, 2026 | clinvar |