TGFBR2 NM_003242.6(TGFBR2):c.340G>C (p.Glu114Gln)

CI-VAR-00156179Explore in graph →p.Glu114GlnNM_003242.6:c.340G>CClinVar 927079 rs771551560

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
927079	Uncertain significance/Uncertain risk allele	criteria provided, multiple submitters, no conflicts	2	Familial thoracic aortic aneurysm and aortic dissection; Loeys-Dietz syndrome 2; Colorectal cancer, hereditary nonpolyposis, type 6; Malignant tumor of esophagus; Diabetic retinopathy	germline	6	Jan 05, 2026	clinvar