Variant · Snv
HTRA2 NM_013247.5(HTRA2):c.937C>T (p.Leu313=)
CI-VAR-00154583Explore in graph →p.Leu313=NM_013247.5:c.937C>TClinVar 895797 rs766035905
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-06
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260908-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 895797 | Uncertain significance | criteria provided, single submitter | 1 | Parkinson disease 13, autosomal dominant, susceptibility to; Clear cell carcinoma of kidney | germline | 2 | Jan 13, 2018 | clinvar |