Variant · Deletion

STK11 NM_000455.5(STK11):c.291-10_922del

CI-VAR-00152019Explore in graph →NM_000455.5:c.291-10_922delClinVar 845797

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
845797	Likely pathogenic	criteria provided, single submitter	1	Peutz-Jeghers syndrome	germline	1	Mar 18, 2019	clinvar

Nomenclature

Record

Gene: STK11
Type: Deletion
HGVS c.: NM_000455.5:c.291-10_922del
Assembly: GRCh38
Position: chr19:1218406-1222986
Ref / Alt: CTCTGTCCCAGGGAAATTCAACTACTGAGGAGGTTACGGCACAAAAATGTCATCCAGCTGGTGGATGTGTTATACAACGAAGAGAAGCAGAAAATATATCCTTTCCGGTGTTGGGACCGCGGGGCCTCCGTGGGAGGGGCTGGGGCCCTGGGTCCGCCTGCCTCGAGGCCTGCTCCTCTTCCCGTCTCCTTGAAGGAGACTGGCACACGAGGGCCGTGGCCTTCCCTGGTTCCCCGGAAGTCAGCCATTGTGGCAATGGCTGCGCAGCTTGCTGAAAGGGGCCCTGAGCCCTGGCCCCTGTGTCTTGGGCCCGTGGGGTGTCAAGTCCCTTTTTTCTCAGAGTCTCCTCCCAGGCTAACCAGGGGTGTAGCCACGGTCTGCCTGAGACAGGCCACGCGGGCTGACCGTTGTGGGCCATTTTGGTCGTGGCTGGGCGTGTCCTCGTGTCATCTGTGGACACCCCCATGGGTCTTACGGGCACAGCCTCCCTACGGGGACTTTGCTTCCTAAGGCCCTGTGCCCAGAGCAAGAGCCAGAAGTGGTCCTGAGGCTGGGGCTGTGTTCCCTGAGCCACGCGGTCAGGGGCCCTGGGACCGTCCTGCATGGGCCCGAGCCTGCTTGGGGGGGCGTCCAGGAGGCACCATCCCCCGCCCATGGGCAGGGTGGGGGACGTGAGCCCCGCAGGAACGCTGCCCCAAGAGTCAGCCCTGTCCTCCCCTTCCCCGTAGGCTCCTTCCTCCTGGGACGCTGGGGCCCCTGGGCCTTTTCAGAGGGGTGGCTGAGGGCAGGGTGGGCCCTGGTCCCGAGGAGGGGCAAGGTGGGTGCAGAGGGTCCCTCCAGAGCCCCTTTTCTGGCCCCCGTGCTCCCTGGGCCTGTGAGTGGGGCCGCCCCCTGAGCTGTGTGTCCTTAGCGCCCCACGTATATGGTGATGGAGTACTGCGTGTGTGGCATGCAGGAAATGCTGGACAGCGTGCCGGAGAAGCGTTTCCCAGTGTGCCAGGCCCACGGGTGCGTGCGCGGGGCAGGGGCCAGGGTGGGGCGGGGGCCGGGGGCCAGGCAGGGCAGGCTCCTTTCCGTGAGGCCACACTGCTTGTCCTGATATTCATTGACATGAAGGCCCAAGTTTTTTTGTTTTTTTGTTTTTTTGTGTTTTTTTTCGAGATGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAATGGTGCGATCTCGGCTCACTGCAAGCTCCGCCTCCGAGGTTCACGCCATTCTTCTGCCTCAGCTTCCCGAGTAGCTGGGATTACAGGCGCCCGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCAAACTCCTGACCTCGTGATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCTACCACGCCCGGCCTTGTAAAGGCCCAAGTTTTTAAAAACAGTTTTGGGGTCCCCCATGTGTGGCATCCACAGGCAGGGCTGCTGCCAACCTCCCGCCTCCATCTTTGCTGGGCCTGCTGCCTGAGGCCAGTGGCCTGCTTCCAGCCCATCGCTGGCAGCCGCCTGCCCTGACCAGATCTCCTGGATGCAGGTCTGTGGCCTCAGAGTCAGGGCCCCTTGCTGCTGCAGGACCACAGGGGCAGGGAGGGGCCTGCTGTTCCAGCAAGACTTTGGGGTGCAGCCGGCCTGTGGCCCACAGGAAAATGAGACCTGTGGACATCCGGGGCCCTGCCAGACGTGGCTCGGCCGGACGAGGGTGGCCACTGCAGGCGCAGGTGTGGCTCCCTGCTGGACCTAGCCTTTCCTCTGTCCTGTGTGCCTGGACTTCTGTGACTTCCCAGCTGGGCCTGTGGTGTTTGGGAGGCTCCCAGGCAGCTGCAAAGGGGACCCCTGTGAGGGGCAGGGAGGCCTCGGCCCCAGGACGGGTGTGTGCTGCCCGCAGGTACTTCTGTCAGCTGATTGACGGCCTGGAGTACCTGCATAGCCAGGGCATTGTGCACAAGGACATCAAGCCGGGGAACCTGCTGCTCACCACCGGTGGCACCCTCAAAATCTCCGACCTGGGCGTGGCCGAGGTAGGCACGTGCTAGGGGGGGCCCTGGGGCGCCCCCTCCCGGGCACTCCCTGAGGGCTGCACGGCACCGCCACAGGCACTGCACCCGTTCGCGGCGGACGACACCTGCCGGACCAGCCAGGGCTCCCCGGCTTTCCAGCCGCCCGAGATTGCCAACGGCCTGGACACCTTCTCCGGCTTCAAGGTGGACATCTGGTCGGCTGGGGTCACCCTGTAAGTGCCCCGCCCCCCCGGGCACTCACCACACGCACACTCCGAGGGGCCTCTGCGTCTTGGGCAGCTGCCGGCCTGTGGGCGCAGGGCGTGGCCACCGGCCCAGACCCTCTCTGGCCACAGCCGCTAGGGGGTGCTTACTTTATGGAAATGTAACTCATACGGCAGATGGTGGTTCACCCGTGTGAAGTGCAGCCTGGCCCGTCAGGGATCTTCACAGAGTGGCACGGCCGACCCTCCTCCCAGAGCCCCACAGGGAAGCTGGGCGGGTGACAGCAGCTCCAGGCCCCTTCCCCGGGTGGGTCCAGAGGACACTCCCCTCCTACCCCGTAGCCTCCACTAGTGGAAGGTGGTGAAGACAGAGGTGTCCTTGAGTCCACAGGGCCTCTGGTCCAGCAGCCACGGGACGCCTCTGTCCCTGGGGTAGAGCTGGGGCTCCTAGGGCGTCAACCACCTTGACTGACCACGCCTTTCTTCCCTCCCCTCGAAATGAAGCTACAACATCACCACGGGTCTGTACCCCTTCGAAGGGGACAACATCTACAAGTTGTTTGAGAACATCGGGAAGGGGAGCTACGCCATCCCGGGCGACTGTGGCCCCCCGCTCTCTGACCTGCTGAAAGGTGGGAGCCTCATCCCTCTGCCCGCAGCCCCAGGGAGGCGGGGCTTTTGTGCAGAAATGTAGGGTTGGGGGTGTCAGGTGGGGGGCTATTGGCCCCGAGACCCCAGCAGGCATTGAGAGGACTGAGTGGAGAGGCCGACCTCCCCGCAGGGCCTGGTTTGCCAGGTCCCTCAGCTCCACCCTGCTTCTGGGCCCTGTTCACCCTCCGAACTCCCACCCCAGAGGGCAGTGCTGCCCTGCGCCTCCCCCAGCCCCACCCTCGGGGGCTCCCTGGCTTGCAGGGTCTGTCAGGGTTGTCCTGCTGCACTTCCTACGCATGGCAGCAGGTGGCACTGGCCGTCCGTCCATCTGCCCAGTGGCCTTGGGAGAACGGAACCGCCCTGGCCGTCCAGCCCAGCCCTGTCTCCCTGCCAGCCGCGCACAGGCTGTCCCCGGCATGTCCCAGGAGTGGAGTGGCCTCTGTCAGGGAGACCGCCTGTGCGCGGGGTCCCCCTTAGGAGCGTCCAGGTATCACCCAGGGCCTGACAACAGAGGCTGGGCAGGCGGGGACGGTTGGTGGGGTCTCAGGCCTGTGCCCAGCTGACAGGCTCCTCGCCGGCTTCTCCTCAGGGATGCTTGAGTACGAACCGGCCAAGAGGTTCTCCATCCGGCAGATCCGGCAGCACAGGTGAGCGGCCCCTGGGGGCAGTGGGGCCGAGGCTGCAGGGAGGCCGGCCATGTGGGCAGCTGGTTGAGCGGGCGCTAGAGCAGGGCGTGGTGGGGGTGCCAGGCTGGGCTGGGGCCAGACCCCGTGCAGCGCCCGCAGTTCTCGGGGCCCGAGTGGGGTCTCTGGGCAGTGTCCTGTTACCGGCCAGACCCAGGCGCCTTGTCCGAACTGGGGTCTGAGTGAGGACATGCGTCCGTCCCTGCCCTAGGCATGGAGATGCGCCAGGAAGGGCACAGCTGGTCCCAAACACTGGCGAGAGCCTCTCTTTTTCCCCTCCTCCTGGGGCTCCCAGCAGCAGGGTGTGGCTGGGATCCAGCCCAGGGCCCCCAGCTCCATGACAGGGAAGACAGAGCAGCGGACGGGGTCAGCAGGCCCCACAGTGCCGCCTCCCTCACTTCGTGGGCTCTGCTCCTCTGCACCAGCCCCTGGAGGCCCTTGAGCCGTCTGCTGGAGCCCCTCCGAGCCCCGAGGCCACCCACTGAGACCGGCTCTGGGAGTGGGAGTGTCCGGACCCCTGAGGCGCTGGTGCTGATTGTGCCTTGGGGGTCTCTGCACAGCTCGGGTCATCTGGGCGCCTGGCGGGGACTGGGGCTGCCCCCCGATAGCCTCCTGGGCTGGGATGTGCTCAGGGCCCCCCAGACCCCCTTCTGGCCTTTGCTGGCTTTGCAGCCAGCATCCATCTGGTGGGTGCTGGCTTCTGAGTGCCACCTGGGACACAGGCCTCAGGGTGGAGGGGACATCTGTCAGGCTTGGAGTCAGGTCAGCCTGCCTGCTCCTAGAGGACATGGCTGAGCTTCTGTGGTCACAGCCACCCCTTGCACGGCCTGGTCCCAGCTCCTGAGTGTGTGGCAGGTACCCTGGGCCCAGAGGAGCTGGGTCGGAAAACTGGACCGCCCTGGTGCCAGCCTGACAGGCGCCACTGCTTCTGGGCGTTTGCAGCT → C