WWOX NM_016373.4(WWOX):c.689A>C (p.Gln230Pro)

CI-VAR-00134940Explore in graph →p.Gln230ProNM_016373.4:c.689A>CClinVar 813767 rs199628364

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
813767	Pathogenic/Likely pathogenic	criteria provided, multiple submitters, no conflicts	2	Developmental and epileptic encephalopathy, 28; Developmental and epileptic encephalopathy, 1; Autosomal recessive spinocerebellar ataxia 12; Abnormality of the nervous system; Early Infantile Epileptic Encephalopathy, Autosomal Recessive; Malignant tumor of esophagus; WWOX-related disorder	germline	16	Jul 16, 2025	clinvar