RUNX1 NM_001754.5(RUNX1):c.508+1G>A

CI-VAR-00134912Explore in graph →NM_001754.5:c.508+1G>AClinVar 812739 rs1601515718

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
812739	Pathogenic	reviewed by expert panel	3	Thrombocytopenia; Hereditary thrombocytopenia and hematologic cancer predisposition syndrome; Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with RUNX1; Uterine corpus endometrial carcinoma; RUNX1-related disorder	germline	6	Aug 31, 2022	clinvar