MME NM_007289.4(MME):c.1040A>G (p.Tyr347Cys)

CI-VAR-00134650Explore in graph →p.Tyr347CysNM_007289.4:c.1040A>GClinVar 809558 rs138218277

Curated evidence

Evidence by cancer (0 items)

Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.

Data not yet available

No curated evidence item references this variant yet.

ClinVar

Clinical significance (1)

ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.

clinvarCurated1 interpretation · review status and star rating as assigned by ClinVar.

Variation	Clinical significance	Review status	Stars	Conditions	Origin	Submitters	Last evaluated	Source
809558	Uncertain significance	criteria provided, multiple submitters, no conflicts	2	Spinocerebellar ataxia 43; Hereditary breast ovarian cancer syndrome; Charcot-Marie-Tooth disease axonal type 2T	germline	15	Jun 09, 2026	clinvar