Variant · Snv
CDK13 NM_003718.5(CDK13):c.2180C>T (p.Thr727Ile)
CI-VAR-00127028Explore in graph →p.Thr727IleNM_003718.5:c.2180C>TClinVar 788670 rs140848307
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-24
- Retrieved
- Sep 29, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260929-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 788670 | Likely benign | criteria provided, multiple submitters, no conflicts | 2 | Congenital heart defects, dysmorphic facial features, and intellectual developmental disorder; CDK13-related disorder; Chronic lymphocytic leukemia/small lymphocytic lymphoma; Clear cell carcinoma of kidney; Ovarian serous cystadenocarcinoma; Thymoma; Cervical cancer | germline | 8 | Dec 13, 2025 | clinvar |