Variant · Snv
CCNB2 NM_004701.4(CCNB2):c.267G>A (p.Lys89=)
CI-VAR-00126638Explore in graph →p.Lys89=NM_004701.4:c.267G>AClinVar 777248 rs35033821
Curated evidence
Evidence by cancer (0 items)
Grouped by cancer context first, then therapy. The same variant can be sensitizing in one cancer and irrelevant in another — contexts are never merged. 50 items per page; a cancer group may continue on the next page.
Data not yet available
No curated evidence item references this variant yet.
ClinVar
Clinical significance (1)
ClinVar interpretations are shown as structured records — significance, review status, star rating, conditions — never flattened into one word.
clinvarProvenance
- Source
- NCBI ClinVar (variant_summary)
- Dataset
- ClinVar variant_summary
- Version
- 2026-09-14
- Retrieved
- Sep 15, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- database
- License
- Public domain (US Government work, NCBI/NLM); acknowledgment requested
- Run
- ING-CLINVAR-20260915-000001
| Variation | Clinical significance | Review status | Stars | Conditions | Origin | Submitters | Last evaluated | Source |
|---|---|---|---|---|---|---|---|---|
| 777248 | Benign | criteria provided, multiple submitters, no conflicts | 2 | Uterine corpus endometrial carcinoma; Clear cell carcinoma of kidney; Uveal melanoma; Lung cancer; Cervical cancer; Uterine carcinosarcoma; Thymoma; Thyroid cancer, nonmedullary, 1; Melanoma; Malignant lymphoma, large B-cell, diffuse; Sarcoma; Ovarian serous cystadenocarcinoma; Acute myeloid leukemia; Malignant tumor of esophagus; Colorectal cancer; Gastric cancer; Hepatocellular carcinoma; Nonpapillary renal cell carcinoma | germline | 3 | Jun 26, 2018 | clinvar |